Evidence map›Paper›PMID 31970659›Full record

ArticleAdvances in therapy2020

The Benefits of Micronized Purified Flavonoid Fraction (MPFF) Throughout the Progression of Chronic Venous Disease.

Andrew N Nicolaides

2 registry-linked trialsOpen access · hybridAbstract readEditorial
In one paragraph

Article in Advances in therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04434274 unknown statusnot on this map

Efficacy of MIcronized Purified Flavonoid Fraction-Based Phlebotropic Therapy After Endovenous MechanO-Chemical Ablation

TypeobservationalSponsorBelarusian State Medical UniversityRan2019 to 2022Enrolled100ConditionsVaricose Veins, SurgeryArmsMicronized Purified Flavonoid Fraction
NCT06753448 completednot on this mapstarted 2024, after this paper: background citation

Efficacy of Diosmin and Hesperidin on Early Rehabilitation After Primary Total Knee Arthroplasty

Typeobservational_patient_registrySponsorAnkara Etlik City HospitalRan2024 to 2025Enrolled190ConditionsTotal Knee Arthroplasty, Venous Insufficiency of LegArmsDiosmin and Hesperidin Combination
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Bioactive Compounds inCurrent pharmaceutical design · 2024
    Review
  4. No More Venous Ulcers-What More Can We Do?Journal of clinical medicine · 2023
    Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Andrew N NicolaidesDepartment of Surgery, University of Nicosia Medical School, Nicosia, Cyprus. anicolai@cytanet.com.cy.
University of Nicosia · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At the 2019 European Venous Forum in Zurich Switzerland, a symposium entitled "State of the art: benefits of MPFF throughout CVD progression" was held to discuss the developing treatment strategies for patients at all stages of chronic venous disease (CVD). At the early stages of CVD, management should be focused on preventing disease progression through lifestyle changes and conservative treatment; treatment can also include venoactive drugs (VAD) such as micronized purified flavonoid fraction (MPFF; Daflon

Indexed as

Chronic DiseaseCompression BandagesDiosminDisease ProgressionEuropeFlavonoidsHumansSclerotherapyVaricose UlcerVascular DiseasesVenous InsufficiencyDiosminFlavonoidsChronic venous diseaseChronic venous refluxEndovenous ablationSclerotherapyVenoactive drugsVenous leg ulcers

Identifiers

PMID31970659
PMCPMC7004432
OpenAlexW3002420877

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.