ArticleEnvironmental science and pollution research international2020
Copper oxychloride-induced testicular damage of adult albino rats and the possible role of curcumin in healing the damage.
Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 19 citations in OpenAlex.
- Silymarin attenuates oxidative, inflammatory and apoptotic damage induced by a fungicide mixture in rat liver, kidney and brain.Toxicology reports · 2026Article
- Protective effects of curcumin against chemical-induced toxicity in the male reproductive system: a systematic review.Frontiers in pharmacology · 2026Review
- Excess copper exposure and male reproductive toxicity: molecular mechanisms and potential interventions.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Review
- The effect of dietary supplementation with Nigella sativa (black seeds) mediates immunological function in male Wistar rats.Scientific reports · 2021Article
- Ameliorative effects of crocin on tartrazine dye-induced pancreatic adverse effects: a biochemical and histological study.Environmental science and pollution research international · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current research study investigated the effect of 80 mg/kg b.wt./day curcumin (cur) against 50, 100, and 200 mg/kg copper oxychloride (COC) for 90 days induced testicular damage using histological, ultrastructural, and biochemical techniques. Histological and cellular abnormalities have been noted in seminiferous tubules of COC-treated group and treated group with Cur- and COC-treated group. The biochemical result showed that serum testosterone was significantly decreased in COC-treated rats and Cur COC-treated rats compared with the control groups. Testes copper content and malondialdehyde was increased, whereas the testes total antioxidant, manganese, ferrous, and zinc levels were decreased (p ≥ 0.05) compared to the control groups. In conclusion, the present work reported that the treatment of rats with 80 mg/kg body weight curcumin prior to treatment with COC did not mitigate the deleterious effects of COC and manifested no signs of protection.
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Registered trials
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