Evidence map›Paper›PMID 31970595›Full record

Trial reportJournal of neuro-oncology2020

Perioperative neurocognitive functions in patients with neuroepithelial intracranial tumors.

Stefanie Bette, Corinna V Gradtke, Jasmin Hernandez Cammardella, Jennifer Albertshauser, Benedikt Wiestler, Melanie Barz, Bernhard Meyer, Claus Zimmer, Yu-Mi Ryang, Florian Ringel and 1 more

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Journal of neuro-oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Stefanie BetteDepartment of Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.ORCID http://orcid.org/0000-0001-7027-6617
Corinna V GradtkeDepartment of Neurosurgery, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
Jasmin Hernandez CammardellaDepartment of Neurosurgery, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
Jennifer AlbertshauserDepartment of Neurosurgery, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
Benedikt WiestlerDepartment of Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
Melanie BarzDepartment of Neurosurgery, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
Bernhard MeyerDepartment of Neurosurgery, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
Claus ZimmerDepartment of Neuroradiology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
Yu-Mi RyangDepartment of Neurosurgery, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
Florian RingelDepartment of Neurosurgery, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
Jens GemptDepartment of Neurosurgery, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany. jens.gempt@tum.de.
TUM Klinikum · DEJohannes Gutenberg University Mainz · DEUniversity Hospital Augsburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to assess perioperative neurocognitive functions in patients with surgery for intracranial neuroepithelial tumors.

methodsSeventy-one patients [38 male, 33 female, mean age 47.2 years (range 18 to 81)] with surgery for an intracranial neuroepithelial tumor were included in this prospective single-center study. Mini-mental status examination (MMSE) and extensive neurocognitive testing (divided into the categories attention, memory, and executive functions and adjusted for age, sex, and education) were performed pre-(t

resultsPostoperative deterioration was observed in 5 of 39 subtests of extensive neurocognitive testing in all 3 categories, whereas no improvement was shown. Patients with WHO Grade I tumors showed no deterioration of cognitive functions. Patients with WHO Grade II and III tumors showed significantly worse results in the executive functions category patients with WHO Grade IV tumors showed deterioration in the attention category. Significantly worse functional independence was recorded postoperatively and during follow-up (P < 0.001). Patients reported poorer physical health (SF 36, P = 0.001) at t

conclusionsAfter surgery on an intracranial neuroepithelial tumor, early postoperative deterioration of neurocognitive functions, functional independence and physical health occur. Similar results were also shown during follow-up suggesting that these effects are not only due to postoperative systemic factors or fatigue. This knowledge might improve perioperative surveillance of neurocognitive functions.

Indexed as

AdolescentAdultAgedAged, 80 and overBrain NeoplasmsFemaleHumansMaleMental Status and Dementia TestsMiddle AgedNeoplasms, NeuroepithelialNeurosurgical ProceduresPerioperative PeriodPostoperative ComplicationsPostoperative PeriodProspective StudiesAttentionExecutive functionsMemoryNeurocognitionNeuroepithelial tumorsSurgery

Identifiers

PMID31970595
OpenAlexW3001166901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.