Evidence map›Paper›PMID 31970564›Full record

Trial reportLasers in medical science2020

Photobiomodulation as an adjunctive therapy for alveolar socket preservation: a preliminary study in humans.

Kleber Arturo Vallejo Rosero, Rui Manuel Freire Sampaio, Maria Cristina Zindel Deboni, Luciana Corrêa, Márcia Martins Marques, Emanuela Prado Ferraz, Maria da Graça Naclério-Homem

3 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05911607 nacompletednot on this mapstarted 2021, after this paper: background citation

Influence of Photobiomodulation Therapy (PBMT) as an Adjunctive Therapy in Alveolar Socket Preservation Preceding Dental Implant Placement

TypeinterventionalSponsorCairo UniversityRan2021 to 2022Enrolled20ConditionsExtraction Socket HealingArmsLow power laser
NCT06150456 phase1completednot on this mapstarted 2022, after this paper: background citation

Evaluation of Alveolar Bone Preservation After Molar Extraction Using Photobiomodulation Combined With Grafting With Scaffold Biomaterial: Clinical, Randomized, Triple-blind Study.

TypeinterventionalSponsorUniversity of Nove de JulhoRan2022 to 2022Enrolled60ConditionsExtracting Own Teeth, Bone SubstitutesArmsextraction, low level laser therapy, Plenum® OSShp and Plenum® Guide
NCT06164626 phase1unknown statusnot on this mapstarted 2023, after this paper: background citation

Evaluation of Alveolar Bone Preservation After Early Molar Extraction Using Photobiomodulation Combined With Grafting With Scaffold Biomaterial: Clinical, Randomized, Triple-blind Study.

TypeinterventionalSponsorUniversity of Nove de JulhoRan2023 to 2024Enrolled60ConditionsExtracting Own Teeth, Bone SubstitutesArmsExtraction, low level laser therapy, Plenum® OSShp and Plenum® Guide
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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  5. Light stimuli attenuates inflammatory activation in primary bone marrow-derived macrophages.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Kleber Arturo Vallejo RoseroSchool of Dentistry, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-0865-7368
Rui Manuel Freire SampaioSchool of Dentistry, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-0892-5238
Maria Cristina Zindel DeboniSchool of Dentistry, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-2966-6039
Luciana CorrêaSchool of Dentistry, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-5774-0750
Márcia Martins MarquesSchool of Dentistry, Ibirapuera University, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-9398-1252
Emanuela Prado FerrazSchool of Dentistry, University of São Paulo, São Paulo, Brazil. emanuelaferraz@usp.br.ORCID https://orcid.org/0000-0001-6833-4865
Maria da Graça Naclério-HomemSchool of Dentistry, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-1329-1698
Universidade de São Paulo · BRCentral University of Ecuador · ECUniversidade Ibirapuera · BR

Funding

No -
6 · The paper itself

Abstract

Bone remodeling results in loss of alveolar bone height and thickness. Photobiomodulation (PBM) based on photochemical stimulation by low-intensity lasers emerges as an adjunctive therapy for alveolar socket preservation. Our study aimed to evaluate the effects of PBM therapy on alveolar bone repair. Twenty healthy patients in need of bilateral extraction of lower molars were enrolled in this split-mouth randomized and blind clinical trial. The extraction sites were randomly selected to receive either the PBM therapy with a CW GaAIAs diode laser (808 nm; 0.028 mm

Indexed as

Low-Level Light TherapyAdultAgedBiopsyFemaleHumansImaging, Three-DimensionalLasers, SemiconductorMaleMiddle AgedTooth SocketTreatment OutcomeYoung AdultAlveolar socket preservationBoneComputed microtomographyPhotobiomodulation therapy

Identifiers

PMID31970564
OpenAlexW3002127956

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.