Evidence map›Paper›PMID 31970518›Full record

ArticleEuropean journal of applied physiology2020

Biological variation of arginine vasopressin.

Kurt J Sollanek, Jeffery S Staab, Robert W Kenefick, Samuel N Cheuvront

Abstract read
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In one paragraph

Article in European journal of applied physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kurt J SollanekDepartment of Kinesiology, Sonoma State University, 1801 East Cotati Avenue, Rohnert Park, CA, 94928, USA.
Jeffery S StaabU.S. Army Research Institute of Environmental Medicine, 10 General Greene Ave, Building 42, Natick, MA, 01760, USA. Jeffery.s.staab.civ@mail.mil.ORCID http://orcid.org/0000-0003-0080-1441
Robert W KenefickU.S. Army Research Institute of Environmental Medicine, 10 General Greene Ave, Building 42, Natick, MA, 01760, USA.
Samuel N CheuvrontU.S. Army Research Institute of Environmental Medicine, 10 General Greene Ave, Building 42, Natick, MA, 01760, USA.
U.S. Army Research Institute of Environmental Medicine · USSonoma State University · US

Funding

Medical Research and Materiel Command N/A
6 · The paper itself

Abstract

purposeThere is growing interest in the measurement of plasma levels of arginine vasopressin (AVP) for the assessment of mild dehydration. However, the principles of biological variation have not been applied to the study of AVP and understanding biological variation of AVP may provide insights regarding measurement thresholds. The purpose of this investigation was to determine the biological variation of AVP in healthy euhydrated individuals to understand the potential for establishing both static and/or change thresholds of importance.

methodsWe studied 29 healthy volunteers (24 men and 5 women) while controlling for hydration and pre-analytical factors. All subjects completed between 2-8 trials where biological variation was determined using widely published methods. We determined the intraindividual, interindividual, and analytical coefficients of variation (CV

resultsAVP did not reach the IH threshold required to be considered useful in the dynamic assessment of physiological deviations from normal. AVP levels approached the II threshold required to be considered useful in the static assessment of physiological deviations from normal.

conclusionsThis analysis demonstrates that AVP assessment is unlikely to yield useful information about hydration status.

Indexed as

AdolescentAdultAlgorithmsArginine VasopressinFemaleHealthy VolunteersHumansMaleOrganism Hydration StatusYoung AdultArginine VasopressinDehydrationHydrationIndex of heterogeneityIndex of individualityReference change value

Identifiers

PMID31970518
OpenAlexW3002513630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.