Evidence map›Paper›PMID 31970511›Full record

Observational studyHeart and vessels2020

Prognostic role of bronchial asthma in patients with heart failure.

Mina Nakayama, Masaaki Konishi, Eiichi Akiyama, Yukiko Morita, Yuma Fukutomi, Naoki Nakayama, Takeshi Takamura, Kouichi Tamura, Kazuo Kimura

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Heart and vessels, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Mina NakayamaDepartment of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Masaaki KonishiDepartment of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan. m_koni@yokohama-cu.ac.jp.ORCID http://orcid.org/0000-0002-3020-7526
Eiichi AkiyamaDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
Yukiko MoritaDepartment of Cardiology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.
Yuma FukutomiDepartment of Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.
Naoki NakayamaDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
Takeshi TakamuraDepartment of Cardiology, National Hospital Organization Sagamihara National Hospital, Sagamihara, Japan.
Kouichi TamuraDepartment of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.
Kazuo KimuraDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
National Sagamihara Hospital · JPYokohama City University Medical Center · JPYokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are few reports investigating the relationship between bronchial asthma (BA) and heart failure (HF). We hypothesized BA may have impact on prognosis in patients with HF. Among 323 consecutive outpatients with HF, 191 patients without chronic obstructive pulmonary disease were analyzed. Twenty patients had BA, most of whom (80.0%) had preserved left ventricular ejection fraction (LVEF ≥ 50%). The use of β-blockers was less frequent (55.0% vs 83.0%. p = 0.01), systolic blood pressure (133 ± 22 vs 120 ± 17 mmHg, p = 0.003), and heart rate (83 ± 14 vs 74 ± 15 bpm, p = 0.02) were higher in patients with BA than those without BA. During median follow up of 24 months, 45 (23.6%) experienced primary outcome defined as a composite of all-cause death, nonfatal myocardial infarction, nonfatal ischemic stroke, and unexpected hospitalization due to HF. Multivariate Cox regression analysis revealed that the presence of BA was independently associated with the occurrence of primary outcome (hazard ratio 3.08, 95% CI 1.42-6.71, p = 0.004). In the subgroup analysis of patients with preserved LVEF, patients with BA exhibited worse outcomes (p = 0.03 by log-rank). Patients with HF complicated by BA, most of whom had preserved LVEF, exhibited worse outcomes than those without BA.

Indexed as

HemodynamicsVentricular Function, LeftAgedAged, 80 and overAsthmaDisease ProgressionFemaleHeart Disease Risk FactorsHeart FailureHospitalizationHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk AssessmentBronchial asthmaHeart failureHeart failure with preserved left ventricular ejection fractionSystemic inflammation

Identifiers

PMID31970511
OpenAlexW3002135440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.