Evidence map›Paper›PMID 31970303›Full record

ArticleHeliyon2020

Down-regulation of TGF-β, VEGF, and bFGF in vascular endothelial cells of chicken induced by a brittle star (

Saeed Ataei Kachooei, Roya Rahmani, Nasrin Zareh, Fatemeh Donyadideh, Saba Ataei Kachooei, Mohammad Nabiuni, Sajjad Yazdansetad

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Saeed Ataei KachooeiDepartment of Poultry Diseases, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.
Roya RahmaniDepartment of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Karaj, Iran.
Nasrin ZarehDepartment of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Karaj, Iran.
Fatemeh DonyadidehDepartment of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Karaj, Iran.
Saba Ataei KachooeiDepartment of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Karaj, Iran.
Mohammad NabiuniDepartment of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Karaj, Iran.
Sajjad YazdansetadDepartment of Microbiology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Kharazmi University · IRAgricultural Research & Education Organization · IRGolestan University · IRRazi Vaccine and Serum Research Institute · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Great attention has been focused on the discovery of anti-angiogenic natural and synthetic compounds to be finally used as or at least a part of the treatment of tumors. The marine ecosystems provide diversity in natural chemicals with the potential of being exploited as medicines in the treatment of diseases. Several studies have investigated Ophiuroids as a source of anti-tumor and anti-metastatic organisms. Here, we described the inhibitory effects of an ethanolic crude extract of brittle star (

Indexed as

Angiogenesis inhibitorsCancer researchCell biologyChorioallantoic membraneHyperplasiaMolecular biologyOphiocoma erinaceusPharmaceutical scienceVascular endothelial growth factor

Identifiers

PMID31970303
PMCPMC6965705
OpenAlexW2999754221

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.