Evidence map›Paper›PMID 31970234›Full record

ArticleAmerican journal of clinical and experimental urology2019

Comparison of the effect of antibiotic-lock and ethanol-lock methods on infection rate in children with hemodialysis catheter.

Alireza Merikhi, Alaleh Gheysari, Yahya Madihi, Mehryar Mehrkash, Enayatollah Poorebrahim, Leila Ghambarinia

Open access · greenAbstract read
In one paragraph

Article in American journal of clinical and experimental urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Ethanol Lock for Prevention of CVC-Related Bloodstream Infection in Pediatric Patients: A Systematic Review and Meta-Analysis.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alireza MerikhiChild Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Contagious Diseases, Isfahan University of Medical Sciences Isfahan, Iran.
Alaleh GheysariChild Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Contagious Diseases, Isfahan University of Medical Sciences Isfahan, Iran.
Yahya MadihiChild Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Contagious Diseases, Isfahan University of Medical Sciences Isfahan, Iran.
Mehryar MehrkashChild Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Contagious Diseases, Isfahan University of Medical Sciences Isfahan, Iran.
Enayatollah PoorebrahimChild Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Contagious Diseases, Isfahan University of Medical Sciences Isfahan, Iran.
Leila GhambariniaChild Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Contagious Diseases, Isfahan University of Medical Sciences Isfahan, Iran.
Isfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemodialysis catheter-related infection has a high incidence and complications. Antibiotic-lock or ethanol-lock can be used to prevent such infections. The aim of this study was to compare the effectiveness of antibiotic-lock and ethanol-lock methods in children undergoing hemodialysis and to evaluate the optimality of these methods.

methodsIn this cohort clinical study, 25 children with chronic renal failure with hemodialysis catheter referring to Imam-Hossein Hospital in Isfahan, Iran, in 2016-2017 were studied. During two 6-month course, their catheter was locked first with antibiotics for 6 months, and then with ethanol for 6 months. Side effects, para-clinical findings and infectious species were also studied and data were analyzed.

resultsIn the first 6 months, 44% of the subjects and in the second 6 months, 12% of the subjects had catheter infections. The rate of infection, redness and catheter site sensitivity at the second 6-month course was significantly lower compared to the first 6-month course (P<0.05).

conclusionBoth Antibiotic-lock and ethanol-lock are useful and practical methods for controlling infection. However, according to the results of this study, the ethanol-lock method seems to be more effective than antibiotic-lock in controlling the infection in children with hemodialysis catheter.

Indexed as

antibiotic lockcatheterchildrenethanol lockHemodialysis

Identifiers

PMID31970234
PMCPMC6971476
OpenAlexW3013358630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.