ReviewMovement disorders clinical practice2020
Physical Activity, Exercise, and Physiotherapy in Parkinson's Disease: Defining the Concepts.
Review in Movement disorders clinical practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Changes of brain-derived neurotrophic factor (BDNF) levels after different exercise protocols: a systematic review of clinical studies in Parkinson's disease.Frontiers in physiology · 2024Pooled it
- Physical exercise and its effects on people with Parkinson's disease: Umbrella review.PloS one · 2023Pooled it
- Efficacy and Characteristics of the Stimuli of Action Observation Therapy in Subjects With Parkinson's Disease: A Systematic Review.Frontiers in neurology · 2020Pooled it
- Effects of basic and dual-task training programs on physical function in Parkinson's disease: The PARKEX study.PloS one · 2026Trial
- Changes in proBDNF and Mature BDNF Levels After Medium-Intensity Functional Motor Rehabilitation Program in Patients with Parkinson's Disease.International journal of molecular sciences · 2025Trial
- Improving Balance and Gait in Older People with Parkinson's Disease: A Randomized Controlled Trial of Technology-Assisted Rehabilitation Interventions.Bioengineering (Basel, Switzerland) · 2026Article
- Telerehabilitation for people with Parkinson's disease: protocol of a randomised clinical trial of mixed methods.BMJ open · 2025Article
- Factors Associated With the Response to Exercise in Patients With Parkinson's Disease.Journal of movement disorders · 2025Article
- Relationship Between Each of the Four Major Motor Symptoms and At-Home Physical Activity in Individuals with Parkinson's Disease: A Cross-Sectional Study.Neurology international · 2025Article
- Integrating virtual reality into multidisciplinary care for Parkinson's disease: A narrative review.Journal of Parkinson's disease · 2025Review
- The Impact of Physical Activity on Negative Affect and Sleep Quality in Adolescents: Network Analysis.Psychology research and behavior management · 2025Article
- Post-Physical Therapy 4-Month In-Home Dynamic Standing Protocol Maintains Physical Therapy Gains and Improves Mobility, Balance Confidence, Fear of Falling and Quality of Life in Parkinson's Disease: A Randomized Controlled Examiner-Blinded Feasibility Clinical Trial.Journal of frailty, sarcopenia and falls · 2024Article
- System-level barriers account for non-compliance to physiotherapy among persons with Parkinson's disease at the Korle Bu Teaching Hospital, Ghana: an explanatory mixed-method study.African health sciences · 2024Article
- Review
- Exercise Habits in People with Parkinson's: A Multinational Survey.Movement disorders clinical practice · 2024Article
- Review
- Survey of the Knowledge, Attitudes, and Practices of Neurologists Regarding Exercise in Parkinson's Disease.Journal of clinical neurology (Seoul, Korea) · 2024Article
- Group-based exercise for Parkinson's: a qualitative study of participants and partners' perceptions of an exercise class delivered through a community-university collaboration.BMC geriatrics · 2024Article
- Tango and physiotherapy interventions in Parkinson's disease: a pilot study on efficacy outcomes on motor and cognitive skills.Scientific reports · 2024Article
- The Interplay of Sports and Nutrition in Neurological Health and Recovery.Journal of clinical medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExercise is gaining extreme relevancy as a new therapeutic intervention for Parkinson's disease (PD). However, the frequent misuse of the concepts exercise, physiotherapy, and physical activity limits the possibility of summarizing research findings. This review aims to clarify these concepts and summarize the evidence on exercise in PD.
methodsWe critically appraised physical activity-related concepts and conducted a systematic review of clinical trials evaluating exercise interventions in PD. Additionally, we discussed the implications for PD clinical practice and research.
resultsExercise is a subset of physical activity, and a major component of physiotherapy for PD management, having as the main goal to improve physical fitness. The appraisal of the 83 identified clinical trials found high variability in exercise interventions. Multimodal exercise was the most studied, and 60 minutes, two times/week for 12 weeks, the most reported prescription parameters.
conclusionThe best available evidence recommends increasing physical activity levels in PD. Exercise and physiotherapy programs seem the most efficacious strategies to achieve this goal. As a result of the heterogeneity in the type and manner exercise is prescribed, it is not possible to propose strong recommendations for exercise in PD. We believe that, in addition to the clarification of concepts here presented, a collaborative and rigorous work of different areas of knowledge is needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.