ArticleBrain plasticity (Amsterdam, Netherlands)2019
Higher Cardiorespiratory Fitness is Associated with Reduced Functional Brain Connectivity During Performance of the Stroop Task.
Article in Brain plasticity (Amsterdam, Netherlands), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Not All Stroop-Type Tasks Are Alike: Assessing the Impact of Stimulus Material, Task Design, and Cognitive Demand via Meta-analyses Across Neuroimaging Studies.Neuropsychology review · 2025Pooled it
- Physical fitness moderates the association between brain network impairment and both motor function and cognition in progressive multiple sclerosis.Journal of neurology · 2023Trial
- The effort hypothesis at the heart of the virtuous circle.EXCLI journal · 2025Review
- Cardiorespiratory Fitness and Sleep, but not Physical Activity, are Associated with Functional Connectivity in Older Adults.Sports medicine - open · 2024Article
- Associations between cardiorespiratory fitness and executive function in Chinese adolescents.Scientific reports · 2024Article
- Consistent activation differences versus differences in consistent activation: Evaluating meta-analytic contrasts.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Pre-diabetes is associated with altered functional connectivity density in cortical regions of the default-mode network.Frontiers in aging neuroscience · 2022Article
- The Association of Obesity and Cardiorespiratory Fitness in Relation to Cognitive Flexibility: An Event-Related Potential Study.Frontiers in human neuroscience · 2022Article
- Genetic Influence Underlying Brain Connectivity Phenotype: A Study on Two Age-Specific Cohorts.Frontiers in genetics · 2021Article
- Cardiorespiratory Fitness and Performance in Multiple Domains of Executive Functions in School-Aged Adolescents.Frontiers in physiology · 2021Article
- Exercise Effects on Cognitive Function in Humans.Brain plasticity (Amsterdam, Netherlands) · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough higher cardiorespiratory fitness (CRF) has been linked to better executive function, the mechanisms by which this occurs remain a matter of speculation. One hypothesis is that higher CRF is associated with elevated top-down control in which brain regions processing task-relevant information are up-regulated and brain regions processing task-irrelevant information are down-regulated.
methodsWe tested this top-down hypothesis in 50 young adults (μ age = 25.22 ± 5.17 years) by measuring CRF via a graded maximal exercise test and performing functional Magnetic Resonance Imaging (fMRI) during a color-word Stroop task. We used task-evoked functional connectivity, quantified from a psychophysiological interaction analysis (PPI), to test our hypotheses that (a) higher CRF would be associated with greater connectivity between control centers (i.e., prefrontal and parietal areas) and visual feature centers (i.e., occipital areas) that are involved with processing task-relevant stimulus dimensions (i.e., color), and (b) higher CRF would be associated with lower connectivity between control centers and visual feature centers that are involved with processing task-irrelevant dimensions of the stimuli (i.e., word processing areas).
resultsControlling for sex and BMI, we found, consistent with our second hypothesis, that higher CRF was associated with reduced functional connectivity between parietal and occipital areas involved in the task-irrelevant dimension of the task (i.e., word form areas). There were no associations between CRF and functional connectivity with the prefrontal cortex or evidence of heightened connectivity between attentional control and visual feature centers.
conclusionsThese results suggest that CRF associations with executive functioning might be explained by CRF-mediated differences between brain regions involved with attentional control (parietal regions) and the down-regulation of regions involved with processing task-irrelevant stimulus features (occipital regions).
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