Evidence map›Paper›PMID 31969995›Full record

ArticleJournal of advanced research2020

Far infrared radiation induces changes in gut microbiota and activates GPCRs in mice.

Imran Khan, Sabrina Pathan, Xiao Ang Li, Wai Kit Leong, Wei Lin Liao, Vincent Wong, W L Wendy Hsiao

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Imran KhanState Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau.
Sabrina PathanState Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau.
Xiao Ang LiState Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau.
Wai Kit LeongState Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau.
Wei Lin LiaoState Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau.
Vincent WongState Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau.
W L Wendy HsiaoState Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau.
Macau University of Science and Technology · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Far infrared radiation (FIR) has been widely used to treat chronic diseases and symptoms; however, the underlying mechanism remains unclear. As gut microbiota (GM) markedly impact the host's physiology, making GM a potential target for the therapeutic evaluation of FIR. C57BL/6J mice were exposed to five times of 2 min-FIR exposure on the abdomen, with a two-hour interval of each exposure within one day. Fecal samples were collected on day one and day 25 after the FIR/control treatment, and the extracted fecal DNAs were evaluated using ERIC-PCR and 16S amplicon sequencing. Host's G-protein coupled receptors (GPCR) were analyzed using qRT-PCR. FIR induced immediate changes in the GM composition. A prompt and significant (p < 0.05) reduction in the abundance of phylum Deferribacteres (comprised of several pathogens) was observed in the FIR-irradiated mice compared to the control group. Contrarily, FIR exposure induced beneficial genera such as

Indexed as

16S amplicon sequencingERIC-PCRFar infraredGPCRGut microbiotaSCFA

Identifiers

PMID31969995
PMCPMC6965508
OpenAlexW2997622191

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.