Evidence map›Paper›PMID 31969916›Full record

ArticleJournal of contemporary brachytherapy2019

A new implant device to prevent edema-associated underdosage in high-dose-rate interstitial brachytherapy of mobile tongue cancer.

Ken Yoshida, Tadayuki Kotsuma, Hironori Akiyama, Hideya Yamazaki, Tadashi Takenaka, Koji Masui, Yutaka Tsujimoto, Naoya Murakami, Yasuo Uesugi, Taiju Shimbo and 7 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of contemporary brachytherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Ken YoshidaDepartment of Radiation Oncology, Osaka Medical College, Takatsuki, Osaka, Japan.
Tadayuki KotsumaDepartment of Radiation Oncology, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Hironori AkiyamaDepartment of Oral Radiology, Osaka Dental University, Osaka, Japan.
Hideya YamazakiDepartment of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Tadashi TakenakaDepartment of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Koji MasuiDepartment of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Yutaka TsujimotoDepartment of Radiology, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Naoya MurakamiDepartment of Radiation Oncology, National Cancer Center Hospital, Japan.
Yasuo UesugiDepartment of Rehabilitation Sciences, Faculty of Allied Health Sciences, Kansai University of Welfare Sciences, Japan.
Taiju ShimboDepartment of Radiation Oncology, Osaka Medical College, Takatsuki, Osaka, Japan.
Nobuhiko YoshikawaDepartment of Radiation Oncology, Osaka Medical College, Takatsuki, Osaka, Japan.
Hiroto YoshiokaDepartment of Radiation Oncology, Osaka Medical College, Takatsuki, Osaka, Japan.
Mio NakataDepartment of Radiation Oncology, Osaka Medical College, Takatsuki, Osaka, Japan.
Takumi ArikaDepartment of Oral Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Yuji TakaokaDepartment of Radiation Oncology, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Eiichi TanakaDepartment of Radiation Oncology, National Hospital Organization Osaka National Hospital, Osaka, Japan.
Nikolaos TselisDepartment of Radiation Oncology, Johann Wolfgang Goethe University Frankfurt, Germany.
Osaka Medical and Pharmaceutical University · JPOsaka National Hospital · JPKyoto Prefectural University of Medicine · JPGoethe University Frankfurt · DEKansai University of Welfare Sciences · JPOsaka Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTongue edema is a potential cause of treatment target underdosage in high-dose-rate interstitial brachytherapy (HDR-ISBT) of mobile tongue cancer. To prevent such edema-associated alteration of dosimetry, we developed a special silicon device. In this report we communicate our initial experience with two mobile tongue cancer patients whom we treated using this new device. MATERIAL AND

methodsThe device consists of silicone tubes with a fixed width and scalable length depending on tongue size. These tubes are lined and fixed like a palisade, allowing the device to be used also as a template. The device is placed next to the lateral border of the tongue and on the floor of the mouth. In addition, a vinyl template can be placed on the dorsal tongue surface with both devices combined for implantation guidance. Between June and August 2012, two patients with locally confined tongue cancer were treated.

resultsBetween June and August 2012, two mobile tongue cancer patients classified as cT2N0M0 were treated with HDR-ISBT using the silicone device. They underwent ISBT as monotherapy with fractional doses of 6.0 Gy up to a total physical dose of 54.0 Gy. The D

conclusionsThe described silicone device has the potential to prevent underdosage to the treatment target related to tongue edema. It has been shown to be safe and easy to implement.

Indexed as

high-dose-rate interstitial brachytherapymobile tongue cancersilicone devicetongue edema

Identifiers

PMID31969916
PMCPMC6964338
OpenAlexW3000215981

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.