Evidence map›Paper›PMID 31969703›Full record

ArticleNature2020

Structure of the transcription coactivator SAGA.

Haibo Wang, Christian Dienemann, Alexandra Stützer, Henning Urlaub, Alan C M Cheung, Patrick Cramer

Open access · greenAbstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 162 citations in OpenAlex.

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  20. Characterization of TBP and TAFs in Mungbean (International journal of molecular sciences · 2024
    Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Haibo WangMax Planck Institute for Biophysical Chemistry, Department of Molecular Biology, Göttingen, Germany.
Christian DienemannMax Planck Institute for Biophysical Chemistry, Department of Molecular Biology, Göttingen, Germany.
Alexandra StützerMax Planck Institute for Biophysical Chemistry, Bioanalytical Mass Spectrometry, Göttingen, Germany.
Henning UrlaubMax Planck Institute for Biophysical Chemistry, Bioanalytical Mass Spectrometry, Göttingen, Germany.
Alan C M CheungDepartment of Structural and Molecular Biology, Institute of Structural and Molecular Biology, University College London, London, UK.
Patrick CramerMax Planck Institute for Biophysical Chemistry, Department of Molecular Biology, Göttingen, Germany. pcramer@mpibpc.mpg.de.
Max Planck Institute for Biophysical Chemistry · DEUniversitätsmedizin Göttingen · DEUniversity College London · GB

Funding

European Research Council 693023Wellcome Trust 102535Wellcome Trust 102535/Z/13/Z
6 · The paper itself

Abstract

Gene transcription by RNA polymerase II is regulated by activator proteins that recruit the coactivator complexes SAGA (Spt-Ada-Gcn5-acetyltransferase)

Indexed as

Cryoelectron MicroscopySaccharomyces cerevisiaeTranscription, GeneticGene Expression Regulation, FungalHistone AcetyltransferasesHistonesModels, MolecularNucleosomesProtein BindingProtein DomainsProtein SubunitsSaccharomyces cerevisiae ProteinsTATA-Box Binding ProteinTrans-ActivatorsTranscription Factor TFIIDUbiquitinationHistone AcetyltransferasesHistonesNucleosomesProtein SubunitsSaccharomyces cerevisiae ProteinsSAGA complex, S cerevisiaeTATA-Box Binding ProteinTrans-ActivatorsTranscription Factor TFIID

Identifiers

PMID31969703
PMCPMC6994259
OpenAlexW3001272727

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.