ArticleScientific reports2020
Novel human reovirus isolated from children and its long-term circulation with reassortments.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- Non-Cytopathic Mammalian Orthoreovirus Infection Triggers Innate Immune Responses in Human Tonsil-Derived Mesenchymal Stem Cells: Implications for Cell Therapy Quality Control.Tissue engineering and regenerative medicine · 2026Article
- Molecular detection of zoonotic RNA viruses in guinea pigs (One health (Amsterdam, Netherlands) · 2026Article
- Prevalence and Genetic Characterization of Mammalian Orthoreoviruses in Diarrheic Cattle from Guangxi, China.Veterinary sciences · 2026Article
- Isolation and phylogenomic characterization of two novel, dissimilar orthoreoviruses from Northern Alaskan Sea otters (Enhydra lutris kenyoni).Scientific reports · 2026Article
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- Molecular survey of mammalian orthoreovirus and Rotavirus A in Italian dogs and cats.Frontiers in veterinary science · 2026Article
- Isolation and characterization of a novel reassortant strain of Orthoreovirus mammalis from diarrheic pig.Virus genes · 2025Article
- Genome Characterization of Mammalian Orthoreovirus and Porcine Epidemic Diarrhea Virus Isolated from the Same Fattening Pig.Animals : an open access journal from MDPI · 2025Article
- Identification of multiple inter- and intra-genotype reassortment mammalian orthoreoviruses from Japanese black cattle in a beef cattle farm.Scientific reports · 2024Article
- Reovirus infection induces transcriptome-wide unique A-to-I editing changes in the murine fibroblasts.Virus research · 2024Article
- Genetic characterization and pathogenicity in a mouse model of newly isolated bat-originated mammalian orthoreovirus in South Korea.Microbiology spectrum · 2024Article
- Isolation and identification of a novel porcine-related recombinant mammalian orthoreovirus type 3 strain from cattle in Guangxi Province, China.Frontiers in microbiology · 2024Article
- Isolation and genetic characterization of a mammalian orthoreovirus from Vespertilio sinensis in Japan.Archives of virology · 2023Article
- Paired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus.Nature communications · 2023Article
- Isolation, molecular characterization, and disinfectants susceptibility of swine-carried mammalian orthoreoviruses in Japan in 2020-2022.The Journal of veterinary medical science · 2023Article
- The μ2 and λ1 Proteins of Mammalian Reovirus Modulate Early Events Leading to Induction of the Interferon Signaling Network.Viruses · 2022Article
- Intertypic reassortment of mammalian orthoreovirus identified in wastewater in Japan.Scientific reports · 2021Article
- Isolation and characterization of mammalian orthoreovirus type 3 from a fecal sample from a wild boar in Japan.Archives of virology · 2021Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mammalian orthoreovirus (MRV), also known as reovirus, was discovered in the 1950s and became the first reported segmented double-stranded RNA virus. MRVs have since been found in a variety of animal species, including humans. However, reports on MRV infections are scarce due to the rarity of their symptomatic occurrence. In Japanese surveillance studies, MRVs have been detected as gastrointestinal pathogens since 1981, with a total of 135 records. In Osaka City, Japan, MRV was first isolated in 1994 from a child with meningitis, and then in 2005 and 2014 from children with gastroenteritis. Here, we conducted the first molecular characterization of human MRV isolates from Japan and identified a novel human reovirus strain belonging to MRV type 2, designated the MRV-2 Osaka strain. This strain, with all three isolates classified, is closely related to MRV-2 isolates from sewage in Taiwan and is relatively close to an MRV-2 isolate from a bat in China. Our data suggest that the MRV-2 Osaka strain, which has circulated amongst humans in Japan for at least two decades, has spread internationally.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.