Evidence map›Paper›PMID 31969553›Full record

ReviewThe American journal of case reports2020

Chordoma: A Case Report and Review of Literature.

Arish Noor, Poorva Bindal, Miguel Ramirez, James Vredenburgh

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in The American journal of case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Late recurrence of cervical spine chordoma: illustrative case.Journal of neurosurgery. Case lessons · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Exophytic Lumbar Vertebral Body Mass in an Adult with Back Pain.AJNR. American journal of neuroradiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Arish NoorInternal Medicine, University of Connecticut, Farmington, CT, USA.
Poorva BindalInternal Medicine, University of Connecticut, Farmington, CT, USA.
Miguel RamirezDepartment of Radiology, St. Francis Hospital, Hartford, CT, USA.
James VredenburghDepartment of Hematology Oncology, St. Francis Hospital, Hartford, CT, USA.
University of Connecticut · USHartford Financial Services (United States)St. Francis Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Chordoma is a rare, but aggressive bone tumor, primarily affecting the axial skeleton. Systemic chemotherapies are not effective against the tumor, and treatment primarily consists of surgical resection and radiation. Despite these treatment modalities, recurrence is common. Our case highlights the role of afatinib as an effective treatment option in such cases. CASE REPORT We present case of 68-year-old female with chordoma, who underwent multiple surgical resections, radiotherapy session, and had course complication by disease progression on imatinib and local recurrence. She was eventually placed on afatinib with good effect. CONCLUSIONS This article discusses the effectiveness of afatanib as a treatment modality, along with diagnosis, histopathological features, associated genetic aberrations, currently available and upcoming treatment options. Special emphasis is placed on molecular targeted therapy, emerging immunotherapies and use of vaccination in this field.

Indexed as

AfatinibAgedAntineoplastic AgentsChordomaCombined Modality TherapyFemaleHead and Neck NeoplasmsHoarsenessHumansImatinib MesylateMagnetic Resonance ImagingNeoplasm Recurrence, LocalSpinal NeoplasmsAfatinibAntineoplastic AgentsImatinib Mesylate

Identifiers

PMID31969553
PMCPMC6998794
OpenAlexW3002942154

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.