ArticleCancer imaging : the official publication of the International Cancer Imaging Society2020
Intravoxel incoherent motion and ADC measurements for differentiating benign from malignant thyroid nodules: utilizing the most repeatable region of interest delineation at 3.0 T.
Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Differentiating the lung lesions using Intravoxel incoherent motion diffusion-weighted imaging: a meta-analysis.BMC cancer · 2020Pooled it
- Intravoxel Incoherent Motion Diffusion-Weighted Imaging for Quantitative Differentiation of Breast Tumors: A Meta-Analysis.Frontiers in oncology · 2020Pooled it
- Intravoxel Incoherent Motion Diffusion-Weighted Imaging Used to Detect Prostate Cancer and Stratify Tumor Grade: A Meta-Analysis.Frontiers in oncology · 2020Pooled it
- T2* mapping in magnetic resonance imaging for stratifying the hypoxic microenvironment in pancreatic ductal adenocarcinoma: a preliminary study.Quantitative imaging in medicine and surgery · 2026Article
- Optimized dual-source dual-energy computed tomography nomogram model integrating background normalization improves solid thyroid nodules diagnosis.Gland surgery · 2026Article
- Machine learning model incorporating spectral CT quantitative parameters and clinical characteristics for differentiation of benign and malignant thyroid nodules.BMC medical imaging · 2025Article
- Review
- An Enhanced Diagnostic Model for Incidental Hashimoto's Thyroiditis Using T2-Weighted and Diffusion-Weighted Imaging.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Enhancing diagnostic accuracy of American College of Radiology TI-RADS 4 nodules: nomogram models based on MRI morphological features.Quantitative imaging in medicine and surgery · 2025Article
- Histogram analysis of multiple diffusion models for predicting advanced non-small cell lung cancer response to chemoimmunotherapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- Prediction model based on MRI morphological features for distinguishing benign and malignant thyroid nodules.BMC cancer · 2024Article
- Recommendations for improved reproducibility of ADC derivation on behalf of the Elekta MRI-linac consortium image analysis working group.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2023Article
- Diagnosis of benign and malignant thyroid nodules by a dual-layer spectral detector CT-based nomogram.Frontiers in oncology · 2023Article
- Article
- Article
- Dual-source dual-energy computed tomography-derived quantitative parameters combined with machine learning for the differential diagnosis of benign and malignant thyroid nodules.Quantitative imaging in medicine and surgery · 2022Article
- Comparison of the Differential Diagnostic Performance of Intravoxel Incoherent Motion Imaging and Diffusion Kurtosis Imaging in Malignant and Benign Thyroid Nodules.Frontiers in oncology · 2022Article
- Association between IVIM parameters and treatment response in locally advanced squamous cell cervical cancer treated by chemoradiotherapy.European radiology · 2021Article
- Assessment of tissue perfusion of pancreatic cancer as potential imaging biomarker by means of Intravoxel incoherent motion MRI and CT perfusion: correlation with histological microvessel density as ground truth.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021Article
- Epithelial-to-Mesenchymal Transition in Pancreatic Cancer is associated with Restricted Water Diffusion in Diffusion-Weighted Magnetic Resonance Imaging.Journal of Cancer · 2021Article
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Abstract
backgroundThere is a growing need for a reproducible and effective imaging method for the quantitative differentiation of benign from malignant thyroid nodules. This study aimed to investigate the performances of intravoxel incoherent motion (IVIM) parameters and the apparent diffusion coefficient (ADC) in differentiating malignant from benign thyroid nodules derived from the most repeatable region of interest (ROI) delineation.
methodsForty-three patients with 46 pathologically confirmed thyroid nodules underwent diffusion-weighted imaging (DWI) with 8 b values. Two observers measured the intravoxel incoherent motion (IVIM) parameters (D, f and D*) and the apparent diffusion coefficient (ADC), ADC
resultsThe ICC values of all IVIM with W-L ROI delineation were higher than those with S-S ROI delineation, and excellent intra- and interobserver reproducibility was obtained. According to the Bland-Altman plots, the 95% limits of agreement of the IVIM parameters determined by the W-L ROIs revealed smaller absolute intra- and interobserver variability than those determined by S-S ROIs. The D and ADC
conclusionsThe W-L ROI of the thyroid was considered an effective method for obtaining IVIM measurements with excellent reproducibility for differentiating benign from malignant nodules.
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