Evidence map›Paper›PMID 31968527›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Prevalence of Antibiotics Prescription and Assessment of Prescribed Daily Dose in Outpatients from Mexico City.

Ramiro Sánchez-Huesca, Abel Lerma, Rebeca M E Guzmán-Saldaña, Claudia Lerma

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Prescribed daily-dose-based metrics of oral antibiotic use for hospitalized children in Japan.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023
    Article
  6. Article
  7. Study of the indications for macrolide prescriptions in a Colombian populationBiomedica : revista del Instituto Nacional de Salud · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ramiro Sánchez-HuescaCEBECI Farmacología Clínica Sociedad Civil, 06700 Mexico City, Mexico.
Abel LermaInstitute of Health Sciences, Universidad Autónoma del Estado de Hidalgo, 42160 San Juan Tilcuautla, Mexico.
Rebeca M E Guzmán-SaldañaInstitute of Health Sciences, Universidad Autónoma del Estado de Hidalgo, 42160 San Juan Tilcuautla, Mexico.ORCID 0000-0003-0877-4871
Claudia LermaDepartment of Electromechanical Instrumentation, Instituto Nacional de Cardiología Ignacio Chávez, 14080 Mexico City, Mexico.ORCID 0000-0002-4679-7751

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmacoepidemiological research about antibiotics is supported by the World Health Organization (WHO), but data regarding antibiotic prevalence based on actual prescriptions and dosing patterns are insufficient. The aims were: (i) To estimate the prevalence and prescribed daily dose (PDD) of antibiotics in outpatients from Mexico City and (ii) to compare the PDD against the defined daily dose (DDD), as established by the WHO. The study included 685 prescriptions of antibiotics selected randomly from five geographical zones of Mexico City. Drug, dose, frequency, and duration of treatment were obtained from each prescription. PDD values of each antibiotic drug were calculated as the average of the daily doses. Sub-use and overuse were determined by the ratio PDD/DDD for each prescription. The most prescribed antibiotics to outpatients from Mexico City included six pharmacological groups: quinolones (28%), penicillins (23%), cephalosporins (17%), macrolides (10%), lincosamides (9%), and sulfonamides (4%). Both overuse and sub-use were high (55% and 63%, respectively). In conclusion, most of the antibiotics with a high prevalence of prescription also had a high rate of either sub-use or overuse, with prescribed doses that significantly differ with their corresponding DDD. The dosing variation has important clinical implications since it denotes low prescription control.

Indexed as

antibiotics prescriptiondefined daily dosedrug utilizationoutpatientspharmacoepidemiologyprescribed daily dose

Identifiers

PMID31968527
PMCPMC7168224

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.