ArticlePediatric research2020
Preterm birth and the future risk of orthopedic fracture.
Article in Pediatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Preterm birth and birth weight extremes are associated with periodontal disease and tooth loss in the ARIC study.Scientific reports · 2026Article
- Interventions for metabolic bone disease of prematurity: A systematic review and meta-analysis.Metabolism open · 2026Article
- Longitudinal course of bone health from infancy to mid-adulthood in preterm and term-born individuals.Scientific reports · 2025Article
- Preterm birth and risk of bone fractures during childhood and early adulthood.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025Article
- Is there an association between birth characteristics and fractures in young adults? The HUNT Study, Norway.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Maternal diabetes and fracture risk in offspring: a population-based analysis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- Bone mineral density in very low birthweight adults-A sibling study.Paediatric and perinatal epidemiology · 2022Article
- The Effects of Preterm Birth on Musculoskeletal Health-Related Disorders.Journal of clinical medicine · 2021Review
- The epidemiology of infant shaft fractures of femur or humerus by incidence, birth, accidents, and other causes.BMC musculoskeletal disorders · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundPreterm birth occurs during a critical period of bone mineralization. We assessed whether preterm birth increases the risk of childhood fracture.
methodsWe analyzed a cohort of 788,903 infants born between 2006 and 2016 in Quebec, Canada. The exposure was preterm birth (<37 weeks). The outcome was any future hospitalization for fracture before 2018. We estimated hazard ratios (HR) and 95% confidence intervals (CI) for the association of prematurity with fractures in adjusted Cox regression models. We determined if the risk of facture varied by the child's age.
resultsThe incidence of fracture hospitalizations was higher in preterm children than in term children (17.9 vs. 15.3 per 10,000 person-years). Compared with term, preterm children had 1.27 times the risk of femur fracture hospitalization (95% CI 1.01-1.60) and 2.27 times the risk of assault-related fractures (95% CI 1.37-3.76). Preterm children had 2.20 times the risk of femur fracture between 6 and 17 months of age (95% CI 1.45-3.35).
conclusionsPreterm birth is associated with an increased risk of hospitalization for femur fractures and assault-related fractures. Associations are stronger before 18 months of age. Families of preterm children may benefit from counseling and support for fracture prevention during early childhood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.