ArticleAudiology & neuro-otology2020
Interactions between Auditory and Vestibular Modalities during Stimulation with a Combined Vestibular and Cochlear Prosthesis.
Article in Audiology & neuro-otology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Perceptual response characterization in acute vestibular implant stimulation.Journal of neurology · 2025Article
- The impact of bilateral vestibulopathy on quality of life: data from the Antwerp University Hospital registry.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Influence of loud auditory noise on postural stability in autistic children: an exploratory study.Scientific reports · 2025Article
- An investigation into possible interactions in the vestibular system and the cochlea during electrical stimulation.Frontiers in neuroscience · 2025Article
- Article
- The Next Challenges of Vestibular Implantation in Humans.Journal of the Association for Research in Otolaryngology : JARO · 2023Review
- Vestibular prosthesis: from basic research to clinics.Frontiers in integrative neuroscience · 2023Review
- Resting-State Electroencephalography and P300 Evidence: Age-Related Vestibular Loss as a Risk Factor Contributes to Cognitive Decline.Journal of Alzheimer's disease : JAD · 2022Article
- Neurosensory development of the four brainstem-projecting sensory systems and their integration in the telencephalon.Frontiers in neural circuits · 2022Article
- An Implanted Vestibular Prosthesis Improves Spatial Orientation in Animals with Severe Vestibular Damage.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundA combined vestibular and cochlear prosthesis may restore hearing and balance to patients who have lost both. To do so, the device should activate each sensory system independently.
objectivesIn this study, we quantify auditory and vestibular interactions during interleaved stimulation with a combined 16-channel cochlear and 6-channel vestibular prosthesis in human subjects with both hearing and vestibular loss.
methodsThree human subjects were implanted with a combined vestibular and cochlear implant. All subjects had severe-to-profound deafness in the implanted ear. We provided combined stimulation of the cochlear and vestibular arrays and looked for interactions between these separate inputs. Our main outcome measures were electrically evoked slow-phase eye velocities during nystagmus elicited by brief trains of biphasic pulse stimulation of the vestibular end organs with and without concurrent stimulation of the cochlea, and Likert scale assessments of perceived loudness and pitch during stimulation of the cochlea, with and without concurrent stimulation of the vestibular ampullae.
resultsAll subjects had no auditory sensation resulting from semicircular canal stimulation alone, and no sensation of motion or slow-phase eye movement resulting from cochlear stimulation alone. However, interleaved cochlear stimulation did produce changes in the slow-phase eye velocities elicited by electrical stimulation. Similarly, interleaved semicircular canal stimulation did elicit changes in the perceived pitch and loudness resulting from stimulation at multiple sites in the cochlea.
conclusionsThere are significant interactions between different sensory modalities during stimulation with a combined vestibular and cochlear prosthesis. Such interactions present potential challenges for stimulation strategies to simultaneously restore auditory and vestibular function with such an implant.
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