Evidence map›Paper›PMID 31968240›Full record

ArticleCell reports2020

Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5.

Ine Vanderleyden, Sigrid C Fra-Bido, Silvia Innocentin, Marisa Stebegg, Hanneke Okkenhaug, Nicola Evans-Bailey, Wim Pierson, Alice E Denton, Michelle A Linterman

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
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  6. Article
  7. Article
  8. [Changes in percentage of GATA3Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Current Advances in Follicular Regulatory T-Cell Biology.Critical reviews in immunology · 2022
    Review
  15. Review
  16. The dark side of Tregs during aging.Frontiers in immunology · 2022
    Review
  17. TFrontiers in immunology · 2022
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ine VanderleydenLaboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge CB22 3AT, UK.
Sigrid C Fra-BidoLaboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge CB22 3AT, UK.
Silvia InnocentinLaboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge CB22 3AT, UK.
Marisa StebeggLaboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge CB22 3AT, UK.
Hanneke OkkenhaugImaging Facility, Babraham Institute, Cambridge CB22 3AT, UK.
Nicola Evans-BaileyBiological Services Unit, Babraham Research Campus, Cambridge CB22 3AT, UK.
Wim PiersonLaboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge CB22 3AT, UK.
Alice E DentonLaboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge CB22 3AT, UK.
Michelle A LintermanLaboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge CB22 3AT, UK. Electronic address: michelle.linterman@babraham.ac.uk.
Babraham Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/B/000C0407Biotechnology and Biological Sciences Research Council BBS/E/B/000C0427
6 · The paper itself

Abstract

The germinal center (GC) response is critical for generating high-affinity humoral immunity and immunological memory, which forms the basis of successful immunization. Control of the GC response is thought to require follicular regulatory T (Tfr) cells, a subset of suppressive Foxp3

Indexed as

AnimalsForkhead Transcription FactorsGene DeletionGerminal CenterLymphocyte CountMice, Inbred C57BLOrthomyxoviridae InfectionsReceptors, CXCR5T-Lymphocytes, RegulatoryForkhead Transcription FactorsFoxp3 protein, mouseReceptors, CXCR5CXCR5follicular regulatory T cellsgerminal center response

Identifiers

PMID31968240
PMCPMC6988108
OpenAlexW3002926474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.