Evidence map›Paper›PMID 31968076›Full record

ArticleBlood advances2020

P-selectin-deficient mice to study pathophysiology of sickle cell disease.

Margaret F Bennewitz, Egemen Tutuncuoglu, Shweta Gudapati, Tomasz Brzoska, Simon C Watkins, Satdarshan P Monga, Tirthadipa Pradhan-Sundd, Prithu Sundd

Erratum issuedAbstract read
In one paragraph

Article in Blood advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Sickle cell vaso-occlusion: The dialectic between red cells and white cells.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
  16. Article
  17. Review
  18. Review
  19. Live Imaging of the Lung.Current protocols in cytometry · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Margaret F BennewitzPittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Egemen TutuncuogluPittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Shweta GudapatiPittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Tomasz BrzoskaPittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Simon C WatkinsCenter for Biologic Imaging.
Satdarshan P MongaDivision of Experimental Pathology.
Tirthadipa Pradhan-SunddPittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Prithu SunddPittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Funding

Pulmonary arteriole occlusion by platelet-neutrophil micro-emboli in Acute Chest SyndromeR01HL128297 · NHLBI · VERSITI WISCONSIN, INC. · PI SUNDD, PRITHU · 2015 to 2025
$5.4M
Translational Pulmonary Vascular BiologyT32HL110849 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Sruti Shiva · 2012 to 2026
$5.0M
Mechanisms of platelet exosome-mediated acute chest syndrome in sickle cell diseaseR01HL141080 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NEAL, MATTHEW D, NOVELLI, ENRICO M · 2019 to 2022
$3.1M
Request for Zeiss 710 multiphoton 5Live Duoscan MicroscopeS10RR028478 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WATKINS, SIMON C · 2011 to 2011
$1.1M
Request for a Nikon A1R Multiphoton MicroscopeS10OD025041 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WATKINS, SIMON C · 2018 to 2018
$870k
Molecular Mechanism of Sickle Cell Hepatic CrisisK01DK125617 · NIDDK · VERSITI WISCONSIN, INC. · PI PRADHAN-SUNDD, TIRTHADIPA · 2020 to 2024
$736k
Pulmonary arteriole micro-embolism by platelet-neutrophil aggregates promotes sickle cell disease acute chest syndromeF32HL131216 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BENNEWITZ, MARGARET · 2016 to 2016
$38k
NCRR NIH HHS S10 RR028478NHLBI NIH HHS F32 HL131216NHLBI NIH HHS R01 HL128297NHLBI NIH HHS R01 HL141080NHLBI NIH HHS T32 HL110849NIDDK NIH HHS K01 DK125617NIH HHS S10 OD025041
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anemia, Sickle CellAnimalsHumansMaleMiceP-SelectinRatsP-Selectin

Identifiers

PMID31968076
PMCPMC6988409

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.