Evidence map›Paper›PMID 31967794›Full record

ArticleBiomacromolecules2020

Synthesis of Silver Nanoparticles Using Curcumin-Cyclodextrins Loaded into Bacterial Cellulose-Based Hydrogels for Wound Dressing Applications.

Abhishek Gupta, Sophie M Briffa, Sam Swingler, Hazel Gibson, Vinodh Kannappan, Grazyna Adamus, Marek Kowalczuk, Claire Martin, Iza Radecka

Open access · hybridAbstract read
In one paragraph

Article in Biomacromolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 1 pooled it
26.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 1 synthesis or guideline pooled it, 345 citations in OpenAlex.

  1. Antibiotic Nanoparticles-Loaded Wound Dressings AgainstInternational journal of nanomedicine · 2024
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  18. Trends in the Treatment of Chronic Wounds.Current medicinal chemistry · 2025
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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Abhishek GuptaSchool of Pharmacy, Faculty of Science and Engineering, University of Wolverhampton, WV1 1LY Wolverhampton, U.K.ORCID 0000-0001-7901-1818
Sophie M BriffaSchool of Geography, Earth and Environmental Sciences, University of Birmingham, B15 2TT Birmingham, U.K.
Sam SwinglerWolverhampton School of Sciences, Faculty of Science and Engineering, University of Wolverhampton, WV1 1LY, Wolverhampton, U.K.
Hazel GibsonWolverhampton School of Sciences, Faculty of Science and Engineering, University of Wolverhampton, WV1 1LY, Wolverhampton, U.K.
Vinodh KannappanResearch Institute in Healthcare Science, Faculty of Science and Engineering, University of Wolverhampton, WV1 1LY Wolverhampton, U.K.
Grazyna AdamusCentre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, 41-819 Zabrze, Poland.
Marek KowalczukCentre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Sklodowskiej 34, 41-819 Zabrze, Poland.ORCID 0000-0002-2877-7466
Claire MartinDepartment of Biological Sciences, School of Sciences and the Environment, University of Worcester, WR1 3AS Worcester, U.K.ORCID 0000-0002-5497-4594
Iza RadeckaWolverhampton School of Sciences, Faculty of Science and Engineering, University of Wolverhampton, WV1 1LY, Wolverhampton, U.K.ORCID 0000-0003-3257-8803
University of Wolverhampton · GBCentre of Polymer and Carbon Materials · PLUniversity of Birmingham · GBUniversity of Worcester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wounds are often recalcitrant to treatment because of high microbial bioburden and the problem of microbial resistance. Silver is a broad-spectrum natural antimicrobial agent with wide applications extending to proprietary wound dressings. Recently, silver nanoparticles have attracted attention in wound management. In the current study, the green synthesis of nanoparticles was accomplished using a natural reducing agent, curcumin, which is a natural polyphenolic compound that is well-known as a wound-healing agent. The hydrophobicity of curcumin was overcome by its microencapsulation in cyclodextrins. This study demonstrates the production, characterization of silver nanoparticles using aqueous curcumin:hydroxypropyl-β-cyclodextrin complex and loading them into bacterial cellulose hydrogel with moist wound-healing properties. These silver nanoparticle-loaded bacterial cellulose hydrogels were characterized for wound-management applications. In addition to high cytocompatibility, these novel dressings exhibited antimicrobial activity against three common wound-infecting pathogenic microbes

Indexed as

CurcuminCyclodextrinsMetal NanoparticlesAnti-Bacterial AgentsBandagesCelluloseHydrogelsSilverAnti-Bacterial AgentsCelluloseCurcuminCyclodextrinsHydrogelsSilver

Identifiers

PMID31967794
PMCPMC7588018
OpenAlexW3001320941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.