Evidence map›Paper›PMID 31967327›Full record

ReviewJournal of medical virology2020

Emerging coronaviruses: Genome structure, replication, and pathogenesis.

Yu Chen, Qianyun Liu, Deyin Guo

Erratum issued 4 registry-linked trialsAbstract readReview
In one paragraph

Review in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 4 registered trials, which are not on this map. Cited by 1,438 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,438citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04343768 phase2completednot on this map

An Investigation Into Beneficial Effects of Interferon Beta 1a, Compared to Interferon Beta 1b And The Base Therapeutic Regiment in Moderate to Severe COVID-19: A Randomized Clinical Trial

TypeinterventionalSponsorShahid Beheshti University of Medical SciencesRan2020 to 2020Enrolled60ConditionsCOVID-19ArmsHydroxychloroquine, Lopinavir / Ritonavir, Interferon Beta-1A, Interferon Beta-1B
NCT04420260 nacompletednot on this mapstarted 2021, after this paper: background citation

Scheme of Primary Prevention of Infection by COVID-19, in Workers: Phase II Controlled Clinical Trial, to be Carried Out in Medellín-Antioquia

TypeinterventionalSponsorUnidad de Investigación Genética MolecularRan2021 to 2021Enrolled152ConditionsCOVIDArmsGroup A: oropharygeal spray and immunostimulant emulsion, Group D:Placebo oropharyngeal spray + Placebo taken PO
NCT04441502 unknown statusnot on this map

Identification of Predictors for the Evolution of COVID-19 Related Interstitial Pneumonia by Transcriptomic and Seroproteomic Techniques

TypeobservationalSponsorIRCCS Policlinico S. DonatoRan2020 to 2024Enrolled204ConditionsCovid19, Interstitial Pneumonia
NCT04490473 naunknown statusnot on this map

Turkish Validity And Reliability of the SARS-CoV-2 Anxiety Scale

TypeinterventionalSponsorDILEK SAYIKRan2020 to 2021Enrolled300ConditionsAnxiety, SARS-CoV InfectionArmssurvey work
3 · Its place in the literature

Who cites it

1,438 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. MarinePharmaceuticals (Basel, Switzerland) · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

1,378 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Yu ChenState Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China.
Qianyun LiuState Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China.
Deyin GuoCenter for Infection and Immunity Study, School of Medicine, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0002-8297-0814

Funding

China National Science and Technology Major Project #2018ZX10733403Guangdong Zhujiang Talents Program 2017National Natural Science Foundation of China #81620108020 & #81672008Shenzhen Science and Technology Program KQTD20180411143323605
6 · The paper itself

Abstract

The recent emergence of a novel coronavirus (2019-nCoV), which is causing an outbreak of unusual viral pneumonia in patients in Wuhan, a central city in China, is another warning of the risk of CoVs posed to public health. In this minireview, we provide a brief introduction of the general features of CoVs and describe diseases caused by different CoVs in humans and animals. This review will help understand the biology and potential risk of CoVs that exist in richness in wildlife such as bats.

Indexed as

AnimalsBetacoronavirusCommunicable Diseases, EmergingCoronavirusCoronavirus InfectionsCOVID-19Genome, ViralHost SpecificityHumansPneumonia, ViralSARS-CoV-2Viral Nonstructural ProteinsViral Structural ProteinsVirus ReplicationViral Nonstructural ProteinsViral Structural Proteinscoronavirusepidemiologypathogenesisrespiratory tractvirus classificationzoonoses

Identifiers

PMID31967327
PMCPMC7167049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.