Evidence map›Paper›PMID 31967284›Full record

ArticleClinics (Sao Paulo, Brazil)2020

Ultrasound Versus Contrast-Enhanced Magnetic Resonance Imaging for Subclinical Synovitis and Tenosynovitis: A Diagnostic Performance Study.

Zhongtao Bao, Yanchun Zhao, Shuqiang Chen, Xiaoyu Chen, Xiang Xu, Linglin Wei, Meilian Xiong

Open access · goldAbstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhongtao BaoDepartment of Ultrasound, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350000, China.ORCID 0000-0003-2536-6714
Yanchun ZhaoDepartment of Ultrasound, Fujian Provincial Hospital, Fuzhou, Fujian, 350000, China.ORCID 0000-0001-5253-0554
Shuqiang ChenDepartment of Ultrasound, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350000, China.ORCID 0000-0002-4367-9055
Xiaoyu ChenDepartment of Ultrasound, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350000, China.ORCID 0000-0003-1993-4105
Xiang XuDepartment of Ultrasound, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350000, China.ORCID 0000-0002-0102-1837
Linglin WeiDepartment of Ultrasound, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350000, China.ORCID 0000-0002-6975-5394
Meilian XiongDepartment of Imaging, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, 350000, China.ORCID 0000-0002-6621-5384
Fujian Medical University · CNFujian Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesRadiographic manifestations of synovitis (e.g., erosions) can be observed only in the late stage of rheumatoid arthritis. Ultrasound is a noninvasive, cheap, and widely available technique that enables the evaluation of inflammatory changes in the peripheral joint. In the same way, dynamic contrast-enhanced magnetic resonance imaging (MRI) enables qualitative and quantitative measurements. The objectives of the study were to compare the sensitivity and accuracy of ultrasound in detecting subclinical synovitis and tenosynovitis with those of contrast-enhanced MRI.

methodsThe ultrasonography and contrast-enhanced MRI findings of the wrist, metacarpophalangeal, and proximal interphalangeal joints (n=450) of 75 patients with a history of joint pain and morning stiffness between 6 weeks and 2 years were reviewed. The benefits score was evaluated for each modality.

resultsThe ultrasonic findings showed inflammation in 346 (77%) joints, while contrast-enhanced MRI found signs of early rheumatoid arthritis in 372 (83%) joints. The sensitivities of ultrasound and contrast-enhanced MRI were 0.795 and 0.855, respectively, and the accuracies were 0.769 and 0.823, respectively. Contrast-enhanced MRI had a likelihood of 0-0.83 and ultrasound had a likelihood of 0-0.77 for detecting synovitis and tenosynovitis at one time. The two imaging modalities were equally competitive for detecting synovitis and tenosynovitis (p=0.055).

conclusionUltrasound could be as sensitive and specific as contrast-enhanced MRI for the diagnosis of subclinical synovitis and tenosynovitis.

Indexed as

AdultAgedFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedSynovitisTenosynovitisUltrasonographyWrist Joint

Identifiers

PMID31967284
PMCPMC6963161
OpenAlexW3000366000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.