ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2020
Rabies encephalitis and extra-neural manifestations in a patient bitten by a domestic cat.
Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Investigation and Response to a Single Cat Injuring Multiple People - Shandong Province, China, 2026.China CDC weekly · 2026Article
- Equine Rabies in Southern Colombia, 2024-2025.Animals : an open access journal from MDPI · 2026Article
- Extracorporeal membrane oxygenation support for tropical infections: a scoping review.Journal of intensive care · 2026Review
- Reemergence of Human Rabies in an Endemic Peruvian Amazon Region.The American journal of tropical medicine and hygiene · 2025Article
- Application of metagenomics sequencing to diagnose paralytic rabies with stroke-like onset: a case report.Frontiers in medicine · 2025Article
- Review
- Review
- Comparing Intradermal (ID) Rabies Vaccination with Conventional IM Regimen on Humoral Response of New Zealand White Rabbits for the Production of Animal-Derived Polyclonal Antibodies.Veterinary medicine international · 2024Article
- Tracking lethal threat: in-depth review of rabies.Open veterinary journal · 2023Review
- Evaluation of Dynamics, Demography and Estimation of Free-Roaming Dog Population in Herat City, Afghanistan.Animals : an open access journal from MDPI · 2023Article
- Cat rabies in Brazil: a growing One Health concern.Frontiers in public health · 2023Review
- An Overview of Anthropogenic Actions as Drivers for Emerging and Re-Emerging Zoonotic Diseases.Pathogens (Basel, Switzerland) · 2022Review
- Update on lyssaviruses and rabies: will past progress play as prologue in the near term towards future elimination?Faculty reviews · 2020Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rabies encephalitis is a fatal zoonotic viral disease transmitted to humans either by domestic animals like dogs and cats or by wild animals like bats, skunks and raccoons. We present the case of a 25-year-old woman admitted due to behavioral disorders, generalized paresthesiasand acute respiratory deterioration compatible with a respiratory distress syndrome (ARDS) requiring orotracheal intubation, mechanical ventilation and empirical initiation of antibiotic and antiviral therapy. Chest tomography showed pneumomediastinum and changes suggestive of pulmonary infection. In the presence of neurological symptoms, a central nervous system (CNS) infection was suspected and the cerebrospinal fluid showed no pleocytosis, hiperproteinorrachy without glucose consumption; cranial CT scan was normal. During hospitalization, the family reported that the patient was bitten by a cat 30-day prior to the onset of rabies-like symptoms, and the animal was sacrificed. The patient had an unfavorable clinical evolution, with electroencephalographic activity dissociation evidenced by video telemetry. The zoonotic exposure led to the suspected diagnosis of rabies infection. The patient died and the suspected diagnosis was confirmed by histopathology, with presence of Negri bodies on cerebellum Purkinje cells and a positive immunofluorescence test for rabies virus. Both, initial extra-neural manifestations and late reporting of rabies exposure led to delayed diagnosis.
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