Evidence map›Paper›PMID 31966918›Full record

ArticleWorld journal of gastrointestinal oncology2020

Adenosquamous carcinoma may have an inferior prognosis to signet ring cell carcinoma in patients with stages I and II gastric cancer.

Yu-Xin Chu, Hong-Yun Gong, Qin-Yong Hu, Qi-Bin Song

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastrointestinal oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Immunoprofile of adenosquamous carcinoma in gastric cancer.Journal of the Chinese Medical Association : JCMA · 2023
    Article
  5. Review
  6. Primary tumor resection benefited the survival of patients with distant metastatic gastric cancer.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yu-Xin ChuDepartment of Oncology (Division I), Cancer Center, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Hong-Yun GongDepartment of Oncology (Division I), Cancer Center, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Qin-Yong HuDepartment of Oncology (Division I), Cancer Center, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China. rm001223@whu.edu.cn.
Qi-Bin SongDepartment of Oncology (Division I), Cancer Center, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Wuhan University · CNRenmin Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary gastric adenosquamous carcinoma (ASC) is an exceedingly rare histological subtype. Gastric signet ring cell carcinoma (SRC) is a unique subtype with distinct tumor biology and clinical features. The prognosis of gastric ASC

aimTo investigate the clinicopathological characteristics and prognosis of gastric ASC

methodsA cohort of gastric cancer patients was retrospectively collected from the Surveillance, epidemiology, and end results program database. The 1:4 propensity score matching was performed among this cohort. The clinicopathological features and prognosis of gastric ASC were compared with gastric SRC by descriptive statistics. Kaplan-Meier method was utilized to calculate the median survival of the two groups of patients. Cox proportional hazard regression models were used to identify prognostic factors.

resultsTotally 6063 patients with gastric ASC or SRC were identified. A cohort of 465 patients was recruited to the matched population, including 370 patients with SRC and 95 patients with ASC. Gastric ASC showed an inferior prognosis to SRC after propensity score matching. In the post-matching cohort, the median cancer specific survival was 13.0 (9.7-16.3) mo in the ASC group

conclusionASC may have an inferior prognosis to SRC in patients with stages I and II gastric cancer. Our study supports radiotherapy and surgery for the future management of this clinically rare entity.

Indexed as

Adenosquamous carcinomaPrognosisPropensity score matchingSignet ring cell carcinomaSurveillance, Epidemiology, and End resultsSurvival

Identifiers

PMID31966918
PMCPMC6960072
OpenAlexW2995507410

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.