Evidence map›Paper›PMID 31966806›Full record

ArticleInternational journal of clinical and experimental pathology2017

Cisplatin inhibits the growth, migration and invasion of cervical cancer cells by down-regulating IL-17E/IL-17RB.

Jiao Cheng, Chun-Jie Gu, Bing Zhang, Feng Xie, Min-Min Yuan, Ming-Qing Li, Jin-Jin Yu

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jiao ChengDepartment of Obstetrics and Gynecology, The Affiliated Hospital of Jiangnan University Wuxi 214062, Jiangsu Province, People's Republic of China.
Chun-Jie GuDepartment of Obstetrics and Gynecology, The Affiliated Hospital of Jiangnan University Wuxi 214062, Jiangsu Province, People's Republic of China.
Bing ZhangDepartment of Obstetrics and Gynecology, The Affiliated Hospital of Jiangnan University Wuxi 214062, Jiangsu Province, People's Republic of China.
Feng XieLaboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai 200011, People's Republic of China.
Min-Min YuanLaboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai 200011, People's Republic of China.
Ming-Qing LiLaboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai 200011, People's Republic of China.
Jin-Jin YuDepartment of Obstetrics and Gynecology, The Affiliated Hospital of Jiangnan University Wuxi 214062, Jiangsu Province, People's Republic of China.
Jiangnan University · CNObstetrics and Gynecology Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interleukin (IL)-17E mainly produced by immune cells, is a distinct member of the IL-17 cytokine family, which has multifarious immunomodulatory activities. As a potent anticancer drug, cisplatin is commonly used against various types of solid tumors. The present study was performed to investigate whether cisplatin regulates the expression of IL-17E and it receptor IL-17RB, and the role of IL17E in cervical cancer cells

Indexed as

cervical cancer cellscisplatinIL-17EIL-17RBinvasionviability

Identifiers

PMID31966806
PMCPMC6965941
OpenAlexW3026873797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.