Evidence map›Paper›PMID 31966804›Full record

ArticleInternational journal of clinical and experimental pathology2017

CTHRC1 mediates multiple pathways regulating cell invasion, migration and adhesion in glioma.

Peng-Jin Mei, Jin Bai, Fa-An Miao, Chen Chen, Yi-Shuo Zhu, Zhong-Lin Li, Jun-Nian Zheng, Yue-Chao Fan

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
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  5. Recognition of a Novel Gene Signature for Human Glioblastoma.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Peng-Jin MeiDepartment of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University Xuzhou, Jiangsu, China.
Jin BaiJiangsu Key Laboratory of Biological Cancer Therapy, Xuzhou Medical University Xuzhou, Jiangsu, China.
Fa-An MiaoDepartment of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University Xuzhou, Jiangsu, China.
Chen ChenDepartment of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University Xuzhou, Jiangsu, China.
Yi-Shuo ZhuDepartment of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University Xuzhou, Jiangsu, China.
Zhong-Lin LiDepartment of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University Xuzhou, Jiangsu, China.
Jun-Nian ZhengJiangsu Key Laboratory of Biological Cancer Therapy, Xuzhou Medical University Xuzhou, Jiangsu, China.
Yue-Chao FanDepartment of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University Xuzhou, Jiangsu, China.
Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, collagen triple helix repeat containing-1 (CTHRC1) has been reported to be increased in several types of human solid cancers and to be associated with tumor invasion and metastasis. However, the expression and function of CTHRC1 in glioma have not yet been reported. In the present study, we investigated whether CTHRC1 plays a role in glioma pathogenesis. Using the tissue microarray technology, we found that CTHRC1 expression is significantly increased in glioma compared with tumor adjacent normal brain tissue (P<0.01, χ

Indexed as

adhesionCTHRC1gliomainvasionmigration

Identifiers

PMID31966804
PMCPMC6965956
OpenAlexW3027728806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.