Evidence map›Paper›PMID 31966775›Full record

ArticleInternational journal of clinical and experimental pathology2017

Downregulation of serum miR-26a predicts poor clinical outcome of papillary thyroid carcinoma.

Guanghui Ren, Hongtao Li, Xiaoyan He, Jinhui Zhang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Guanghui RenDepartment of General Surgery, Shenzhen Hosipital, Southern Medical University Shenzhen, Guangdong, China.
Hongtao LiDepartment of Thyroid and Breast Surgery, Longgang District Central Hospital of Shenzhen Shenzhen, Guangdong, China.
Xiaoyan HeDepartment of Breast Surgery, The Ninth People's Hospital of Shenzhen City Shenzhen, Guangdong, China.
Jinhui ZhangDepartment of General Surgery, Shenzhen Hosipital, Southern Medical University Shenzhen, Guangdong, China.
Longgang Central Hospital · CNShenZhen People’s Hospital · CNSouthern Medical University Shenzhen Hospital · CNXinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deregulation of miRNAs has been demonstrated to play an important role in the initiation and development of many types of cancers including papillary thyroid carcinoma (PTC). Currently the role of miR-26a and its potential clinical significance for PTC remains unknown. Eighty-four PTC patients and forty healthy controls were enrolled in this study. Quantitative real-time PCR (qRT-PCR) was performed to determine the expression level of serum miR-26a in all the participants. The association between serum miR-26a expression level and clinical outcome of PTC was investigated. Serum miR-26a expression level was reduced in PTC patients compared with the healthy controls (

Indexed as

Papillary thyroid carcinomaprognosisserum miR-26a

Identifiers

PMID31966775
PMCPMC6965458
OpenAlexW3026444519

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.