Evidence map›Paper›PMID 31966756›Full record

ArticleInternational journal of clinical and experimental pathology2017

Upregulation of miR-202-5p promotes cell apoptosis and suppresses cell viability of hypoxia-induced myocardial H9c2 cells by targeting SOX6 to inhibit the activation of the PI3K/AKT/FOXO3a pathway.

Yong Li, Hao Xu, Xingli Fu, Jianguo Ji, Youwei Shi, Yongfang Wang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 69% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yong LiDepartment of Cardiology, Changzhou Wujin People's Hospital, Wujin Hospital Affiliated to Jiangsu University Changzhou, Jiangsu, China.
Hao XuDepartment of Respiratory Medicine, Danyang Hospital Affiliated to Nantong University Danyang, Jiangsu, China.
Xingli FuJiangsu University Health Science Center Zhenjiang, Jiangsu, China.
Jianguo JiDepartment of Cardiology, Changzhou Wujin People's Hospital, Wujin Hospital Affiliated to Jiangsu University Changzhou, Jiangsu, China.
Youwei ShiDepartment of Cardiology, Changzhou Wujin People's Hospital, Wujin Hospital Affiliated to Jiangsu University Changzhou, Jiangsu, China.
Yongfang WangDepartment of Clinical Laboratory, Changzhou Wujin People's Hospital, Wujin Hospital Affiliated to Jiangsu University Changzhou, Jiangsu, China.
Jiangsu University · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the potential role of microRNA-202-5p (miR-202-5p) in regulating myocardial ischemia-caused injury and to explore the underlying mechanisms. Rat embryonic ventricular cardiomyocyte-derived H9c2 cells were treated with hypoxia to generate an

Indexed as

MicroRNA-202-5pmyocardial ischemiaPI3K/AKT/FOXO3a pathwaySOX6

Identifiers

PMID31966756
PMCPMC6965407
OpenAlexW3026311775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.