Evidence map›Paper›PMID 31966634›Full record

ArticleInternational journal of clinical and experimental pathology2017

FTL: a novel predictor in gastric cancer.

Lixiang Zhang, Zhangming Chen, Aman Xu

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lixiang ZhangDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Anhui Medical University Hefei 230022, Anhui, China.
Zhangming ChenDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Anhui Medical University Hefei 230022, Anhui, China.
Aman XuDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Anhui Medical University Hefei 230022, Anhui, China.
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFerritin light chain (FTL) is a functionally distinct composition of ferritin, which is over-expressed and play an important role in multiple human malignancies.

methodsMatched normal and cancerous tissues in 60 gastric cancer (GC) patients were detected for FTL expression using immunohistochemistry staining. The relationship betweent FTL expression and clinicopathological features was analyzed by chi-square test, and the Kaplan-Meier curves and Cox regression analyses were used to calculate the overall survival (OS) characteristics and recurrence-free survival (RFS).

resultsFTL protein was significantly higher in GC tissues than adjacent tissues. Further, FTL expression was not correlative with gender, age, tumor size, tumor location, CEA and AFP level (

conclusionsFTL was an independent risk factor for both RFS and OS, indicating that FTL could be considered as a prognostic factor for GC patients.

Indexed as

Ferritin light chaingastric canceroverall survivalrecurrence-free survival

Identifiers

PMID31966634
PMCPMC6965267
OpenAlexW3026819310

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.