Evidence map›Paper›PMID 31966602›Full record

ArticleInternational journal of clinical and experimental pathology2017

miR-551b-5p increases intracellular Ca

Hua-Jing Ke, Ji Li, Xiao-Juan Yang, Wang Zhang, Tao Su, Tan-Wei Xiong, Jun Song, Pi Liu

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. The Role of MicroRNAs in Pancreatitis Development and Progression.International journal of molecular sciences · 2023
    Review
  3. Review
  4. Micro-organic basis of functional gastrointestinal (GI) disorders: Role of microRNAs in GI pacemaking cells.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hua-Jing KeDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University Nanchang, China.
Ji LiDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University Nanchang, China.
Xiao-Juan YangDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University Nanchang, China.
Wang ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University Nanchang, China.
Tao SuDepartment of Gastroenterology, The Third Hospital of Jingdezhen Jingdezhen, China.
Tan-Wei XiongDepartment of Gastroenterology, Guilin Medical University Guilin, China.
Jun SongDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University Nanchang, China.
Pi LiuDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University Nanchang, China.
Nanchang University · CNGuilin Medical University · CNJingdezhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of the severe acute pancreatitis (SAP)-related miR-551b-5p on intracellular Ca

methodsICCs were isolated from 5-10-day-old rats and cultured

resultsTransfection with the miR-551b-5p mimic or inhibitor resulted in overexpression or downregulation of miR-551b-5p in ICCs, respectively. The overexpression or downregulation of miR-551b-5p had no significant influence on c-Kit mRNA or protein levels. The overexpression of miR-551b-5p significantly increased the intracellular Ca

conclusionmiR-551b-5p increases intracellular Ca

Indexed as

acute pancreatitisc-Kitgastrointestinal motility disorderICCsmicroRNA

Identifiers

PMID31966602
PMCPMC6965254
OpenAlexW3026935827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.