ArticleInternational journal of clinical and experimental pathology2017
Establishment and evaluation of rat trauma hemorrhagic liver injury model.
Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Omega-3 PUFAs Mitigate Polytrauma-Induced Gut-Liver-Lung Inflammation and Organ Dysfunction via GPR120/PPAR-γ.Journal of inflammation research · 2026Article
- Impact of age on liver damage, inflammation, and molecular signaling pathways in response to femoral fracture and hemorrhage.Frontiers in immunology · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trauma hemorrhagic shock is a common and critical disease, which induces multiple organ failure, especially of the liver, when combined with fracture. However, no effective trauma hemorrhagic liver injury model that mimics the real-life condition has been developed so far. This study aims to develop an effective trauma hemorrhagic liver injury model based on a fracture and hemorrhage approach. The levels of the following proteins were determined by the enzyme-linked immunosorbent assay (ELISA) in our fracture and hemorrhage-based model system: serum alanine transaminase (ALT), aspartate aminotransferase (AST), inflammatory cytokines such as interleukin-1β, interleukin-6, and tumor necrosis factor-α, chemokines such as C-C motif ligand 2, C-C motif ligand 5, C-C motif ligand 13, and C-X-C motif ligand 2. Pathological changes in the liver and the numbers of CD45
Indexed as
Identifiers
31966574PMC6965275W3026989262What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.