Evidence map›Paper›PMID 31966559›Full record

ArticleInternational journal of clinical and experimental pathology2017

Inhibitory effect of silymarin on CCl

Xiang-An Zhao, Guang-Mei Chen, Yong Liu, Yu-Xin Chen, Hong-Yan Wu, Jin Chen, Ya-Li Xiong, Chen Tian, Gui-Yang Wang, Bei Jia and 6 more

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Silymarin and Inflammation: Food for Thoughts.Antioxidants (Basel, Switzerland) · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Cerium Oxide Nanoparticles Alleviate Hepatic Fibrosis Phenotypes In Vitro.International journal of molecular sciences · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Xiang-An ZhaoDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine Nanjing, Jiangsu, China.
Guang-Mei ChenDepartment of Infectious Diseases, Affiliated Hospital of Nanjing University of Chinese Medicine Nanjing, Jiangsu, China.
Yong LiuDepartment of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Yu-Xin ChenDepartment of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Hong-Yan WuDepartment of Pathology, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Jin ChenDepartment of Pathology, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Ya-Li XiongDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Chen TianDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Gui-Yang WangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Bei JiaDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Juan XiaDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Jian WangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University Nanjing, Jiangsu, China.
Xiao-Min YanDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Zhao-Ping ZhangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Rui HuangDepartment of Infectious Diseases, Nanjing Drum Tower Hospital, Nanjing University Medical School Nanjing, Jiangsu, China.
Chao WuDepartment of Infectious Diseases, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine Nanjing, Jiangsu, China.
Nanjing Drum Tower Hospital · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been well established that silymarin has hepatoprotective and anti-fibrotic effects. But the mechanisms are poorly understood. In recent years, the role of Ly6C

Indexed as

liver fibrosisLy6Chi monocytesmonocyte chemoattractant protein-1Silymarintransforming growth factor-β1

Identifiers

PMID31966559
PMCPMC6966082
OpenAlexW3026947271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.