Evidence map›Paper›PMID 31966541›Full record

ArticleInternational journal of clinical and experimental pathology2017

Upregulation of P27

Shuguang Wang, Xiaolei Li, Lianqi Yan, Hui Chen, Jingcheng Wang, Yu Sun

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shuguang WangDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Orthopedic Institute, Subei People's Hospital of Jiangsu Province Yangzhou 225001, China.
Xiaolei LiDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Orthopedic Institute, Subei People's Hospital of Jiangsu Province Yangzhou 225001, China.
Lianqi YanDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Orthopedic Institute, Subei People's Hospital of Jiangsu Province Yangzhou 225001, China.
Hui ChenDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Orthopedic Institute, Subei People's Hospital of Jiangsu Province Yangzhou 225001, China.
Jingcheng WangDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Orthopedic Institute, Subei People's Hospital of Jiangsu Province Yangzhou 225001, China.
Yu SunDepartment of Orthopedics, Clinical Medical College of Yangzhou University, Orthopedic Institute, Subei People's Hospital of Jiangsu Province Yangzhou 225001, China.
Northern Jiangsu People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibroblast excessive proliferation is considered as one of the major reasons of epidural fibrosis after laminectomy. Recent studies have shown that mitomycin C (MMC) could successfully reduce the formation of epidural fibrosis by inducing fibroblasts apoptosis. However, the detailed mechanism was still unclear. Increasing evidence indicated that P27

Indexed as

epidural fibrosisfibroblast apoptosisMitomycin CP27Kip1

Identifiers

PMID31966541
PMCPMC6966039
OpenAlexW3026472564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.