Evidence map›Paper›PMID 31966529›Full record

ArticleInternational journal of clinical and experimental pathology2017

Relationship between the 5'UTR of vascular endothelial growth factor polymorphism and retinopathy of prematurity in Chinese premature newborns.

Sheng Zhang, Qiuping Li, Mei Yang, Lu Zhuang, Jie Song, Yupei Zhang, Xiujuan Wei, Zhichun Feng

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 64% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Sheng ZhangAffiliated Bayi Children's Hospital, Army General Hospital Beijing, China.
Qiuping LiAffiliated Bayi Children's Hospital, Army General Hospital Beijing, China.
Mei YangAffiliated Bayi Children's Hospital, Army General Hospital Beijing, China.
Lu ZhuangAffiliated Bayi Children's Hospital, Army General Hospital Beijing, China.
Jie SongAffiliated Bayi Children's Hospital, Army General Hospital Beijing, China.
Yupei ZhangAffiliated Bayi Children's Hospital, Army General Hospital Beijing, China.
Xiujuan WeiAffiliated Bayi Children's Hospital, Army General Hospital Beijing, China.
Zhichun FengAffiliated Bayi Children's Hospital, Army General Hospital Beijing, China.
National Center on Birth Defects and Developmental Disabilities · USBayi Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationship between vascular endothelial growth factor (VEGF) gene polymorphisms and Retinopathy of prematurity (ROP) development in preterm infants of China Han ethnic population.

methodsVEGF gene promoter polymorphisms (-165C/T and -141A/C) were studied in 54 neonates with ROP but not requiring treatment (regressive ROP group), 48 neonates with ROP that requires cryotherapy/photocoagulation (severe ROP group), and in a control group of 62 preterm infants without ROP. Genotyping for VEGF gene promoter was performed by polymerase chain reaction (PCR) and gene sequencing.

resultsIn this study, -165C/T genotype was found to be associated with severe ROP (

conclusionVEGF -165C/T SNP is associated with ROP especial in severe ROP. VEGF -141A/C SNP is not associated with ROP. T

Indexed as

gene polymorphismretinopathy of prematurityVascular endothelial growth factor

Identifiers

PMID31966529
PMCPMC6966069
OpenAlexW3028255476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.