Evidence map›Paper›PMID 31966525›Full record

ArticleInternational journal of clinical and experimental pathology2017

Tumor necrosis factor α promotes HEp-2 cell proliferation via toll-like receptor 4 and NF-κB signaling pathways.

Dezhi Yu, Yang Fang, Menglan Xu, Jinhang Zhu, Kun Li, Kaile Wu, Chuyan Wang, Bing Shen, Juan Du, Yehai Liu

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Dezhi YuDepartment of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital of Anhui Medical University Hefei, Anhui, China.
Yang FangSchool of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Menglan XuSchool of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Jinhang ZhuSchool of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Kun LiDepartment of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital of Anhui Medical University Hefei, Anhui, China.
Kaile WuDepartment of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital of Anhui Medical University Hefei, Anhui, China.
Chuyan WangDepartment of Biological and Environmental Engineering, Hefei University Hefei, Anhui, China.
Bing ShenSchool of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Juan DuDepartment of Physiology, School of Basic Medical Sciences, Anhui Medical University Hefei, Anhui, China.
Yehai LiuDepartment of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital of Anhui Medical University Hefei, Anhui, China.
Anhui Medical University · CNHefei University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laryngeal carcinoma is a serious, life-threatening disease. Tumor necrosis factor α (TNF-α), a proinflammatory cytokine, has complex effects on the proliferation and growth of cancer cells. Previously, we treated a laryngeal cancer cell line (HEp-2) with TNF-α and demonstrated that this treatment suppressed polycystin-2, a transient receptor potential cation channel expression and ATP-induced Ca

Indexed as

human laryngeal squamous cell carcinomaNF-κproliferationRNA-seqtoll-like receptor 4Tumor necrosis factor α

Identifiers

PMID31966525
PMCPMC6966063
OpenAlexW3004601301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.