Evidence map›Paper›PMID 31966491›Full record

ArticleInternational journal of clinical and experimental pathology2017

Apoptotic cell characteristics of rat brain microvascular endothelia induced by different degrees of hypoperfusion.

Shan Tian, Junfa Wu, Ce Li, Bei Zhang, Congyu Jiang, Gang Liu, Ying Chen, Wenting Qin, Fang Li, Yulong Bai and 2 more

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Shan TianDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Junfa WuDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Ce LiDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Bei ZhangDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Congyu JiangDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Gang LiuDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Ying ChenDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Wenting QinDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Fang LiDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Yulong BaiDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Yi WuDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Yulian ZhuDepartment of Rehabilitation, Huashan Hospital, Fudan University Shanghai, China.
Huashan Hospital · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoperfusion is one of the common causes of ischemic stroke. In this study, decreased blood perfusion and neurological damage were confirmed in ischemic rats. Further, the effect of different perfusion was researched in vivo. We found that hypoperfusion promoted the apoptosis of rats brain microvascular endothelial cells, and the more serious of hypoperfusion, the more obvious of apoptosis. At the same time, this process was related to Tie-2 receptor on cell membranes and Caspase-3 apoptotic pathways. Hemodynamics was one factors affecting the cerebral infarction.

Indexed as

apoptosisCerebral hypoperfusionrat brain microvascular endothelial cellsTie-2

Identifiers

PMID31966491
PMCPMC6965888
OpenAlexW3011113278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.