ArticleInternational journal of clinical and experimental pathology2017
Elevated circulating miR-126-3p expression in patients with acute myocardial infarction: its diagnostic value.
Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison of the Clinical Value of miRNAs and Conventional Biomarkers in AMI: A Systematic Review.Frontiers in genetics · 2021Pooled it
- Small Extracellular Vesicles in Cardioprotection, Cardiac Repair, and Regeneration: Cargo Mechanisms, Producer Cell Sources, and Translational Development.Biomedicines · 2026Review
- Alteration of circulating miRNAs during myocardial infarction and association with lipid levels.Laboratory medicine · 2024Article
- Exercise improves cardiac fibrosis by stimulating the release of endothelial progenitor cell-derived exosomes and upregulating miR-126 expression.Frontiers in cardiovascular medicine · 2024Review
- Cardiotoxicity of Electronic Cigarettes and Heat-Not-Burn Tobacco Products-A Problem for the Modern Pediatric Cardiologist.Healthcare (Basel, Switzerland) · 2023Review
- Clinical Application of Serum microRNAs in Atherosclerotic Coronary Artery Disease.Journal of clinical medicine · 2022Review
- Epigenetic regulation in myocardial infarction: Non-coding RNAs and exosomal non-coding RNAs.Frontiers in cardiovascular medicine · 2022Review
- Diagnostic value of cardiac miR-126-5p, miR-134-5p, and miR-499a-5p in coronary artery disease-induced sudden cardiac death.Frontiers in cardiovascular medicine · 2022Article
- Evaluation of VEGF-A in platelet and microRNA-126 in serum after coronary artery bypass grafting.Heart and vessels · 2021Article
- Targeting Epigenetics and Non-coding RNAs in Myocardial Infarction: From Mechanisms to Therapeutics.Frontiers in genetics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute myocardial infarction (AMI) therapy has not remarkably improved due to delay in the diagnosis to a great extent. Circulating microRNAs have shown some potential for diagnosis of cardiovascular diseases. The aim of this study was to estimate the diagnostic value of circulating miR-126-3p for AMI. In our study, circulating miR-126-3p levels were determined by quantitative polymerase chain reaction and the results showed it was 106-fold higher than that in controls, and elevated miR-126-3p was associated with aging through logistic correlation analyses. Receiver-operator characteristic curve was used to evaluate the sensitivity and specificity of miR-126-3p for diagnosis of AMI, indicating that its diagnostic effect was superior to the current clinical markers such as CK, CK-MB, hs-TnI, and MYO. Our results indicate that miR-126-3p in circulation is a potential novel diagnostic biomarker for AMI.
Indexed as
Identifiers
31966451PMC6965822What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.