ArticleInternational journal of clinical and experimental pathology2017
A functional polymorphism rs2257440 in the gene
Article in International journal of clinical and experimental pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Case-Control Study onPharmacogenomics and personalized medicine · 2020Article
- The Role of Decoy Receptor DcR3 in Gastrointestinal Malignancy.Cancer diagnosis & prognosisReview
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe single nucleotide polymorphism (SNP) rs2257440 in exon 1 of the gene METHODS AND
resultsLuciferase reporter assay indicated that MTF-1 elevated the expression of luciferase in the presence of the T allele of rs2257440 while no change in the expression was associated with the C allele of the polymorphism. Chromatin immunoprecipitation further evaluated the binding between the locus harboring the T allele and MTF-1. In the case of the TC genotype, over-expression of MTF-1 elevated
conclusionsOur finding indicates that rs2257440 is a functional SNP. The T allele of rs2257440 can increase
Indexed as
Identifiers
31966445PMC6965886W3028059227What OpenQuestion holds
Registered trials
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