Evidence map›Paper›PMID 31965620›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2020

Photobiomodulation does not influence maturation and mildly improves functional healing of mouse achilles tendons.

Ryan C Locke, Elisabeth A Lemmon, Ellen Dudzinski, Sarah C Kopa, Julianna M Wayne, Jaclyn M Soulas, Luis De Taboada, Megan L Killian

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ryan C LockeDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware.ORCID 0000-0002-8466-3922
Elisabeth A LemmonDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware.
Ellen DudzinskiDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware.
Sarah C KopaDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware.
Julianna M WayneDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware.
Jaclyn M SoulasDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware.
Luis De TaboadaLiteCure, New Castle, Delaware.
Megan L KillianDepartment of Biomedical Engineering, University of Delaware, Newark, Delaware.ORCID 0000-0001-6868-5550
University of Delaware · USDelaware Department of Health and Social Services · US

Funding

Contributions of skeletal muscle loading during rotator cuff maturation and healingR03HD094594 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KILLIAN, MEGAN LEIGH · 2018 to 2019
$156k
Eunice Kennedy Shriver National Institute of Child Health & Human Development R03HD094594NICHD NIH HHS R03 HD094594
6 · The paper itself

Abstract

Tendon rupture can occur at any age and is commonly treated nonoperatively, yet can result in persisting symptoms. Thus, a need exists to improve nonoperative treatments of injured tendons. Photobiomodulation (PBM) therapy has shown promise in the clinic and is hypothesized to stimulate mitochondrial-related metabolism and improve healing. However, the effect of PBM therapy on mitochondrial function during tendon maturation and healing are unknown, and its effect on tendon structure and function remain unclear. In this study, near-infrared light (980:810 nm blend, 2.5 J/cm

Indexed as

Low-Level Light TherapyAchilles TendonAnimalsFemaleGene ExpressionMaleMiceMitochondriaTendon InjuriesAchilles tendonhealinglow-level laser light therapymaturationmitochondriamousephotobiomodulation

Identifiers

PMID31965620
PMCPMC8637462
OpenAlexW3001212020

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.