Evidence map›Paper›PMID 31965525›Full record

SynthesisJournal of general internal medicine2020

Rate of Preventable Mortality in Hospitalized Patients: a Systematic Review and Meta-analysis.

Benjamin A Rodwin, Victor P Bilan, Naseema B Merchant, Catherine G Steffens, Alyssa A Grimshaw, Lori A Bastian, Craig G Gunderson

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of general internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benjamin A RodwinDepartment of Medicine, Yale University School of Medicine, New Haven, CT, USA. Benjamin.Rodwin@yale.edu.ORCID 0000-0001-7771-5416
Victor P BilanDepartment of Medicine, Yale University School of Medicine, New Haven, CT, USA.
Naseema B MerchantDepartment of Medicine, Yale University School of Medicine, New Haven, CT, USA.
Catherine G SteffensVA Connecticut Healthcare System, West Haven, CT, USA.
Alyssa A GrimshawHarvey Cushing/John Hay Whitney Medical Library, Yale University School of Medicine, New Haven, CT, USA.
Lori A BastianDepartment of Medicine, Yale University School of Medicine, New Haven, CT, USA.
Craig G GundersonDepartment of Medicine, Yale University School of Medicine, New Haven, CT, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number of preventable inpatient deaths in the USA is commonly estimated as between 44,000 and 98,000 deaths annually. Because many inpatient deaths are believed to be preventable, mortality rates are used for quality measures and reimbursement. We aimed to estimate the proportion of inpatient deaths that are preventable.

methodsA systematic literature search of Medline, Embase, Web of Science, and the Cochrane Library through April 8, 2019, was conducted. We included case series of adult patients who died in the hospital and were reviewed by physicians to determine if the death was preventable. Two reviewers independently performed data extraction and study quality assessment. The proportion of preventable deaths from individual studies was pooled using a random-effects model.

resultsSixteen studies met inclusion criteria. Eight studies of consecutive or randomly selected cohorts including 12,503 deaths were pooled. The pooled rate of preventable mortality was 3.1% (95% CI 2.2-4.1%). Two studies also reported rates of preventable mortality limited to patients expected to live longer than 3 months, ranging from 0.5 to 1.0%. In the USA, these estimates correspond to approximately 22,165 preventable deaths annually and 7150 deaths for patients with greater than 3-month life expectancy. DISCUSSION: The number of deaths due to medical error is lower than previously reported and the majority occur in patients with less than 3-month life expectancy. The vast majority of hospital deaths are due to underlying disease. Our results have implications for the use of hospital mortality rates for quality reporting and reimbursement. STUDY REGISTRATION: PROSPERO registration number CRD42018095140.

Indexed as

HospitalsInpatientsAdultHospital MortalityHumansLife ExpectancyMedical Errorsmedical errorpatient safetypreventable death

Identifiers

PMID31965525
PMCPMC7351940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.