Evidence map›Paper›PMID 31965523›Full record

ArticleJournal of general internal medicine2020

On-Demand Oral Pre-exposure Prophylaxis with Tenofovir/Emtricitabine: What Every Clinician Needs to Know.

Parya Saberi, Hyman M Scott

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of general internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06159582 (eSTEP), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06159582 nacompletednot on this mapstarted 2024, after this paper: background citation

eSTEP: An Integrated mHealth Intervention to Engage High-risk Individuals Along the Full PrEP Care Continuum

TypeinterventionalSponsorSan Diego State UniversityRan2024 to 2025Enrolled113ConditionsPre-Exposure Prophylaxis (PrEP)ArmseSTEP, Usual Care
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Parya SaberiDivision of Prevention Science, University of California, San Francisco, CA, USA. parya.saberi@ucsf.edu.
Hyman M ScottBridge HIV San Francisco Department of Public Health, San Francisco, CA, USA.
San Francisco Department of Public Health · USUniversity of California, San Francisco · US

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
Improving the HIV PrEP Cascade using an Intervention for Healthcare ProvidersR01NR017573 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SABERI, PARYA · 2017 to 2021
$3.4M
NIMH NIH HHS P30 MH062246NINR NIH HHS R01 NR017573
6 · The paper itself

Abstract

Based on the results of the IPERGAY study, on-demand HIV pre-exposure prophylaxis (PrEP; also known as "non-daily PrEP," "event-driven PrEP," or "2-1-1 PrEP") is being requested more frequently by patients who have intermittent sexual risk or are unable/unwilling to take daily PrEP; therefore, clinicians will be increasingly required to familiarize themselves with its appropriate use. In this perspective, we summarize data related to on-demand PrEP, describe advantages and disadvantages for this alternative dosing strategy, and provide clinical counseling points.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisEmtricitabineHumansTenofovirAnti-HIV AgentsEmtricitabineTenofovir2-1-1clinicianon-demandpre-exposure prophylaxisPrEPtenofovir/emtricitabine

Identifiers

PMID31965523
PMCPMC7174437
OpenAlexW3001993814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.