ArticleArchives of gynecology and obstetrics2020
Altered growth trajectory in children born to mothers with gestational diabetes mellitus and preeclampsia.
Article in Archives of gynecology and obstetrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Association of gestational hypertension and preeclampsia with offspring adiposity: A systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Overlap of Gestational Diabetes Mellitus and Pre-eclampsia: A Scoping Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Review
- Maternal multimorbidity, lifestyle behaviours during pregnancy, and early-childhood growth trajectories: a register-based cohort study.The Lancet regional health. Western Pacific · 2026Article
- Article
- Validation of Variables for Use in Pediatric Obesity Risk Score Development in Demographically and Racially Diverse United States Cohorts.The Journal of pediatrics · 2024Article
- Gestational diabetes mellitus, hypertension, and dyslipidemia as the risk factors of preeclampsia.Scientific reports · 2024Article
- A review of infant growth and psychomotor developmental outcomes after intrauterine exposure to preeclampsia.BMC pediatrics · 2022Review
- Gestational Diabetes Mellitus and Preeclampsia: Correlation and Influencing Factors.Frontiers in cardiovascular medicine · 2022Review
- Sex Discrepancy Observed for Gestational Metabolic Syndrome Parameters and Polygenic Risk Associated With Preschoolers' BMI Growth Trajectory: The Ma'anshan Birth Cohort Study.Frontiers in endocrinology · 2022Article
- Association of higher HbA1c within the normal range with adverse pregnancy outcomes: a cross-sectional study.Acta diabetologica · 2021Article
- Association of early pregnancy warm season exposure and neighborhood heat vulnerability with adverse maternal outcomes: A retrospective cohort study.The journal of climate change and healthArticle
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
Abstract
purposeGestational diabetes mellitus (GDM) and preeclampsia are leading causes of mortality and morbidity in mothers and children. High childhood body mass index (BMI) is among their myriad of negative outcomes. However, little is known about the trajectory of the child BMI exposed to GDM and co-occurring preeclampsia from early to mid-childhood. This study examined the independent and joint impact of GDM and preeclampsia on childhood BMI trajectory.
methodsA population-based sample of 356 mothers were recruited from OB/GYN clinics in New York. Their children were then followed annually from 18 to 72 months. Maternal GDM and preeclampsia status were obtained from medical records. Child BMI was calculated based on their height and weight at annual visits.
resultsHierarchical Linear Modeling was used to evaluate the trajectories of child BMI exposed to GDM and preeclampsia. BMI trajectory by GDM decreased (t ratio = - 2.24, [Formula: see text]0.45, 95% CI - 0.05-0.95, p = 0.07), but the trajectory by preeclampsia increased over time (t ratio = 3.153,[Formula: see text]0.65, 95% CI 0.11-1.18, p = 0.002). Moreover, there was a significant interaction between the two (t ratio = -2.24, [Formula: see text]- 1.244, 95% CI 0.15-2.33, p = 0.02), such that the BMI of children born to mothers with both GDM and preeclampsia showed consistent increases over time.
conclusionsGDM and preeclampsia could be used as a marker for childhood obesity risk and the identification of a high-risk group, providing potential early intervention. These findings highlight the importance of managing obstetric complications, as an effective method of child obesity prevention.
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