Evidence map›Paper›PMID 31965207›Full record

ReviewDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete2020

[New optical examination procedures for the diagnosis of skin diseases].

K Sies, J K Winkler, M Zieger, M Kaatz, H A Haenssle

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

K SiesUniversitätshautklinik Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Deutschland.
J K WinklerUniversitätshautklinik Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Deutschland.
M ZiegerKlinik für Haut- und Geschlechtskrankheiten, SRH Wald-Klinikum Gera, Gera, Deutschland.
M KaatzKlinik für Haut- und Geschlechtskrankheiten, SRH Wald-Klinikum Gera, Gera, Deutschland.
H A HaenssleUniversitätshautklinik Heidelberg, Im Neuenheimer Feld 440, 69120, Heidelberg, Deutschland. holger.haenssle@med.uni-heidelberg.de.
Hautklinik Heidelberg · DESRH Wald-Klinikum Gera · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince the establishment of dermoscopy as a routine examination procedure in dermatology, the spectrum of noninvasive, optical devices has further expanded. In difficult-to-diagnose clinical cases, these systems may support dermatologists to arrive at a correct diagnosis without the need for a surgical biopsy.

objectiveTo give an overview about technical background, indications and diagnostic performance regarding four new optical procedures: reflectance confocal microscopy, in vivo multiphoton tomography, dermatofluoroscopy, and systems based on image analysis by artificial intelligence (AI). MATERIALS AND

methodsThis article is based on a selective review of the literature, as well as the authors' personal experience from clinical studies relevant for market approval of the devices.

resultsIn contrast to standard histopathological slides with vertical cross sections, reflectance confocal microscopy and in vivo multiphoton tomography allow for "optical biopsies" with horizontal cross sections. Dermatofluoroscopy and AI-based image analyzers provide a numerical score, which helps to correctly classify a skin lesion. The presented new optical procedures may be applied for the diagnosis of skin cancer as well as inflammatory skin diseases.

conclusionThe presented optical procedures provide valuable additional information that supports dermatologists in making the correct diagnosis. However, a surgical biopsy followed by dermatohistopathological examination remains the diagnostic gold standard in dermatology.

Indexed as

DermatologySkin DiseasesSkin NeoplasmsDermoscopyHumansMicroscopy, ConfocalSkinConfocal laser scan microscopyDermatofluoroscopyMultiphoton tomographyNoninvasive diagnosticsScreening

Identifiers

PMID31965207
OpenAlexW3003031160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.