Evidence map›Paper›PMID 31965189›Full record

ArticleThe Journal of clinical endocrinology and metabolism2020

Antimullerian Hormone and Impending Menopause in Late Reproductive Age: The Study of Women's Health Across the Nation.

Joel S Finkelstein, Hang Lee, Arun Karlamangla, Robert M Neer, Patrick M Sluss, Sherri-Ann M Burnett-Bowie, Karin Darakananda, Patricia K Donahoe, Sioban D Harlow, Sarah H Prizand and 10 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 88 citations in OpenAlex.

  1. Pooled it
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  14. Heavy Metals and Trajectories of Anti-Müllerian Hormone During the Menopausal Transition.The Journal of clinical endocrinology and metabolism · 2024
    Article
  15. Article
  16. Review
  17. Body Composition Changes Over the Menopausal Transition in Women With and Without Human Immunodeficiency Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  18. Article
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 1 country.

Joel S FinkelsteinEndocrine Unit, Massachusetts General Hospital, Boston, MA.
Hang LeeBiostatistics Center, Massachusetts General Hospital, Boston, Massachusetts.
Arun KarlamanglaDivision of Geriatrics, UCLA School of Medicine, Los Angeles, California.
Robert M NeerEndocrine Unit, Massachusetts General Hospital, Boston, MA.
Patrick M SlussDepartment of Clinical Pathology, Massachusetts General Hospital, Boston, Massachusetts.
Sherri-Ann M Burnett-BowieEndocrine Unit, Massachusetts General Hospital, Boston, MA.
Karin DarakanandaEndocrine Unit, Massachusetts General Hospital, Boston, MA.
Patricia K DonahoePediatric Surgical Research Laboratories, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Sioban D HarlowDepartment of Epidemiology, University of Michigan, Ann Arbor, Michigan.
Sarah H PrizandEndocrine Unit, Massachusetts General Hospital, Boston, MA.
Hadine JoffeDepartment of Psychiatry and Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Ajay KumarAnsh Labs, Webster, Texas.
Deborah E MartinDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Daniel McConnellCentral Ligand Assay Satellite Services (CLASS) Laboratories, University of Michigan, Ann Arbor, Michigan.
Steffenie MerrilatDepartment of Epidemiology, University of Michigan, Ann Arbor, Michigan.
Anthony MorrisonAnsh Labs, Webster, Texas.
Lisa M PastoreDepartment of Obstetrics and Gynecology and Reproductive Medicine, Stony Brook University, Stony Brook, New York.
John F RandolphDepartment of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Michigan, Ann Arbor, Michigan.
Gail A GreendaleDivision of Geriatrics, UCLA School of Medicine, Los Angeles, California.
Nanette SantoroDepartment of Obstetrics and Gynecology, University of Colorado Medical School, Aurora, Colorado.
Massachusetts General Hospital · USUniversity of Michigan–Ann Arbor · USUniversity of California, Los Angeles · USHarvard University · USStony Brook University · USUniversity of Colorado Denver · USUniversity of Pittsburgh · US

Funding

The Study of Women's Health Across the Nation (SWAN): The Impact of Midlife and the Menopause Transition on Health and Functioning in Early Old AgeU19AG063720 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHERRI-ANN M BURNETT-BOWIE, Maria Mori Brooks · 2020 to 2026
$61.3M
WOMENS HEALTH ACROSS THE NATION--COORDINATING CENTERU01AG012553 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROOKS, MARIA MORI · 1994 to 2019
$37.7M
University of Michigan ERC-supplement (TRT)T42OH008455 · OH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NEITZEL, RICHARD L · 2005 to 2025
$32.3M
SWAN Repository IVU01AG017719 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HARLOW, SIOBAN D · 2000 to 2020
$25.0M
WOMENS HEALTH ACROSS THE NATION--ENDOCRINE LABU01AG012495 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCCONNELL, DANIEL S · 1994 to 2018
$18.8M
WOMENS HEALTH ACROSS THE NATION--PITTSBURGHU01AG012546 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MATTHEWS, KAREN · 1994 to 2019
$16.2M
WOMENS HEALTH ACROSS THE NATION--UCDAVISU01AG012554 · NIA · UNIVERSITY OF CALIFORNIA DAVIS · PI GOLD, ELLEN B. · 1994 to 2019
$14.5M
WOMENS HEALTH ACROSS THE NATION--UCLAU01AG012539 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GREENDALE, GAIL A · 1994 to 2018
$13.7M
THE STUDY OF WOMEN'S HEALTH ACROSS THE NATION-MICHIGANU01NR004061 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HARLOW, SIOBAN D · 1994 to 2018
$12.9M
WOMENS HEALTH ACROSS THE NATION--CHICAGOU01AG012505 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI KRAVITZ, HOWARD M · 1994 to 2019
$11.9M
WOMENS HEALTH ACROSS THE NATION--MASSACHUSETTS GENERAL HU01AG012531 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI FINKELSTEIN, JOEL S · 1994 to 2019
$10.7M
Women's Health Across the Nation-New Jersey SiteU01AG012535 · NIA · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI DERBY, CAROL A. · 1994 to 2019
$9.2M
NIA NIH HHS U01 AG012495NIA NIH HHS U01 AG012505NIA NIH HHS U01 AG012531NIA NIH HHS U01 AG012535NIA NIH HHS U01 AG012539NIA NIH HHS U01 AG012546NIA NIH HHS U01 AG012553NIA NIH HHS U01 AG012554NIA NIH HHS U01 AG017719NINR NIH HHS U01 NR004061NIOSH CDC HHS T42 OH008455
6 · The paper itself

Abstract

backgroundA test that helps predict the time to the final menstrual period (FMP) has been sought for many years.

objectiveTo assess the ability of antimullerian hormone (AMH) measurements to predictions the time to FMP.

designProspective longitudinal cohort study.

settingThe Study of Women's Health Across the Nation. PARTICIPANTS AND MEASUREMENTS: AMH and FSH were measured in 1537 pre- or early perimenopausal women, mean age 47.5 ± 2.6 years at baseline, then serially until 12 months of amenorrhea occurred. AMH was measured using a 2-site ELISA with a detection limit of 1.85 pg/mL.

main outcome measureAreas under the receiver operating curves (AUC) for AMH-based and FSH-based predictions of time to FMP, stratified by age. Probabilities that women would undergo their FMP in the next 12, 24, or 36 months across a range of AMH values were assessed.

resultsAUCs for predicting that the FMP will occur within the next 24 months were significantly greater for AMH-based than FSH-based models. The probability that a woman with an AMH <10 pg/mL would undergo her FMP within the next 12 months ranged from 51% at h<48 years of age to 79% at ≥51 years. The probability that a woman with an AMH >100 pg/mL would not undergo her FMP within the next 12 months ranged from 97% in women <48 years old to 90% in women ≥51 years old.

conclusionsAMH measurement helps estimate when a woman will undergo her FMP, and, in general, does so better than FSH.

Indexed as

MenopauseMenstrual CycleReproductionAdultAnti-Mullerian HormoneBiomarkersFemaleFollow-Up StudiesHumansLongitudinal StudiesMiddle AgedPrognosisProspective StudiesUnited StatesWomen's HealthAnti-Mullerian HormoneBiomarkersagingfemale reproductive endocrinologygonadotropinsinhibin/activin/follistatin/AMHmenopauseovaries

Identifiers

PMID31965189
PMCPMC7067546
OpenAlexW3001508918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.