Evidence map›Paper›PMID 31965132›Full record

ArticleBiomaterials science2020

Real time monitoring of biofilm formation on coated medical devices for the reduction and interception of bacterial infections.

Yasin Kurmoo, Andrew L Hook, Daniel Harvey, Jean-Frédéric Dubern, Paul Williams, Stephen P Morgan, Serhiy Korposh, Morgan R Alexander

Open access · hybridAbstract read
In one paragraph

Article in Biomaterials science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Yasin KurmooSchool of Pharmacy, Boots Science Building, University Park, Nottingham NG7 2RD, UK. morgan.alexander@nottingham.ac.uk.
Andrew L Hook
Daniel Harvey
Jean-Frédéric Dubern
Paul Williams
Stephen P Morgan
Serhiy Korposh
Morgan R Alexander
Park University · USUniversity of Nottingham · GB

Funding

Wellcome Trust 103882Wellcome Trust 103884
6 · The paper itself

Abstract

Real time monitoring of bacterial attachment to medical devices provides opportunities to detect early biofilm formation and instigate appropriate interventions before infection develops. This study utilises long period grating (LPG) optical fibre sensors, incorporated into the lumen of endotracheal tubes (ETTs), to monitor in real time, Pseudomonas aeruginosa surface colonisation and biofilm formation. The wavelength shift of LPG attenuation bands was monitored for 24 h and compared with biofilm biomass, quantified using confocal fluorescence microscopy imaging. Biofilm formation was compared on uncoated ETTs and optical fibres, and on a biofilm resistant acrylate polymer, after challenge in an artificial sputum or minimal growth medium (RPMI-1640). The LPG sensor was able to detect a biofilm biomass as low as 81 μg cm

Indexed as

AcrylatesAnti-Bacterial AgentsBiofilmsBiomassMicrobial Sensitivity TestsOptical FibersPolymersPseudomonas aeruginosaPseudomonas InfectionsSurface PropertiesTime FactorsAcrylatesAnti-Bacterial AgentsPolymers

Identifiers

PMID31965132
PMCPMC7613462
OpenAlexW3001019558

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.