Evidence map›Paper›PMID 31965069›Full record

ArticleInternational journal of obesity (2005)2020

Glucose metabolism in brown adipose tissue determined by deuterium metabolic imaging in rats.

Mette Ji Riis-Vestergaard, Christoffer Laustsen, Christian Østergaard Mariager, Rolf F Schulte, Steen Bønløkke Pedersen, Bjørn Richelsen

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of obesity (2005), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Deuterium brain imaging at 7T during DMagnetic resonance in medicine · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Deuterium metabolic imaging - Back to the future.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2021
    Review
  20. Comparison of hyperpolarizedMagnetic resonance in medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mette Ji Riis-VestergaardDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul Jensens Boulevard 99, 8200, Aarhus N, Denmark. metteriis@clin.au.dk.ORCID http://orcid.org/0000-0003-4408-5045
Christoffer LaustsenMR Research Center, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Christian Østergaard MariagerMR Research Center, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Rolf F SchulteGE Healthcare, Munich, Germany.
Steen Bønløkke PedersenDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Bjørn RichelsenDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Palle Juul Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Aarhus University · DKSteno Diabetes Centers · DKSiemens Healthineers (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesBrown adipose tissue (BAT) has gained growing interest as a potential target for treatment of obesity. Currently, the most widely used technique/method for in vivo measurements of BAT activity in humans is SUBJECTS/

methodsMale Sprague-Dawley rats were housed in a cold environment (9 °C, n = 10) or at thermoneutrality (30 °C, n = 11) for 1 week. For imaging rats were anaesthetized, received a

results

conclusionsWe find that DMI can discriminate cold-acclimatised and thermoneutral BAT in rats. This is the first study to evaluate BAT activity by DMI, which may open up for the use of the non-radioactive DMI method for BAT measurements in humans.

Indexed as

AcclimatizationAdipose Tissue, BrownAnimalsCold TemperatureDeuteriumGlucoseMagnetic Resonance ImagingMaleRatsRats, Sprague-DawleyDeuteriumGlucose

Identifiers

PMID31965069
OpenAlexW3001176578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.