ArticleCommunications biology2020
Two-tone distortion in reticular lamina vibration of the living cochlea.
Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Suppression of Low-Frequency Tones in the Organ of Corti Vibrations of the Basal Turn in the Mongolian Gerbil Cochlea.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- The Ins and Outs of Distortion Product Otoacoustic Emission Growth: A Review.Journal of the Association for Research in Otolaryngology : JARO · 2025Review
- Bandpass Shape of Distortion-Product Otoacoustic Emission Ratio Functions Reflects Cochlear Frequency Tuning in Normal-Hearing Mice.Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- The reticular lamina and basilar membrane vibrations in the transverse direction in the basal turn of the living gerbil cochlea.Scientific reports · 2022Article
- Cochlear motion across the reticular lamina implies that it is not a stiff plate.Scientific reports · 2022Article
- Cubic and quadratic distortion products in vibrations of the mouse cochlear apex.JASA express letters · 2022Article
- A Gap-Junction Mutation Reveals That Outer Hair Cell Extracellular Receptor Potentials Drive High-Frequency Cochlear Amplification.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- An outer hair cell-powered global hydromechanical mechanism for cochlear amplification.Hearing research · 2022Article
- Outer hair cell driven reticular lamina mechanical distortion in living cochleae.Hearing research · 2022Review
- Optimizing distortion product otoacoustic emission recordings in normal-hearing ears by adopting cochlear place-specific stimuli.The Journal of the Acoustical Society of America · 2022Article
- Link between stimulus otoacoustic emissions fine structure peaks and standing wave resonances in a cochlear model.The Journal of the Acoustical Society of America · 2022Article
- Distortion Product Otoacoustic Emission (DPOAE) Growth in Aging Ears with Clinically Normal Behavioral Thresholds.Journal of the Association for Research in Otolaryngology : JARO · 2021Article
- The origin of mechanical harmonic distortion within the organ of Corti in living gerbil cochleae.Communications biology · 2021Article
- Intracochlear distortion products are broadly generated by outer hair cells but their contributions to otoacoustic emissions are spatially restricted.Scientific reports · 2021Article
- Does the "Reticular Lamina Nonlinearity" Contribute to the Basal DPOAE Source?Journal of the Association for Research in Otolaryngology : JARO · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
It has been demonstrated that isolated auditory sensory cells, outer hair cells, can generate distortion products at low frequencies. It remains unknown, however, whether or not motile outer hair cells are able to generate two-tone distortion at high frequencies in living cochleae under the mechanical loads caused by surounding tissues and fluids. By measuring sub-nanometer vibration directly from the apical ends of outer hair cells using a custom-built heterodyne low-coherence interferometer, here we show outer hair cell-generated two-tone distortion in reticular lamina motion in the living cochlea. Reticular-lamina distortion is significantly greater and occurs at a broader frequency range than that of the basilar membrane. Contrary to expectations, our results indicate that motile outer hair cells are capable of generating two-tone distortion in vivo not only at the locations tuned to primary tones but also at a broad region basal to these locations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.