Evidence map›Paper›PMID 31964940›Full record

ArticleScientific reports2020

Heart rate variability as an independent predictor for 8-year mortality among chronic hemodialysis patients.

Yu-Ming Chang, Ya-Ting Huang, I-Ling Chen, Chuan-Lan Yang, Show-Chin Leu, Hung-Li Su, Jsun-Liang Kao, Shih-Ching Tsai, Rong-Na Jhen, Chih-Chung Shiao

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  11. Association of coronary artery calcium with heart rate variability in the Brazilian Longitudinal Study of Adult Health - ELSA-Brasil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yu-Ming Chang *Division of Nephrology, Department of Internal Medicine, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongheng S. Rd., Luodong, Yilan, 26546, Taiwan, ROC.
Ya-Ting Huang *Department of Nursing, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongheng S. Rd., Luodong, Yilan, 26546, Taiwan, ROC.
I-Ling ChenDepartment of Nursing, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongheng S. Rd., Luodong, Yilan, 26546, Taiwan, ROC.
Chuan-Lan YangDepartment of Nursing, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongheng S. Rd., Luodong, Yilan, 26546, Taiwan, ROC.
Show-Chin LeuDepartment of Nursing, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongheng S. Rd., Luodong, Yilan, 26546, Taiwan, ROC.
Hung-Li SuDepartment of Nursing, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongheng S. Rd., Luodong, Yilan, 26546, Taiwan, ROC.
Jsun-Liang KaoDivision of Nephrology, Department of Internal Medicine, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongheng S. Rd., Luodong, Yilan, 26546, Taiwan, ROC.
Shih-Ching TsaiDivision of Nephrology, Department of Internal Medicine, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongheng S. Rd., Luodong, Yilan, 26546, Taiwan, ROC.
Rong-Na JhenDivision of Nephrology, Department of Internal Medicine, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongheng S. Rd., Luodong, Yilan, 26546, Taiwan, ROC.
Chih-Chung ShiaoDivision of Nephrology, Department of Internal Medicine, Camillian Saint Mary's Hospital Luodong, No. 160, Zhongheng S. Rd., Luodong, Yilan, 26546, Taiwan, ROC. chungyy2001@yahoo.com.tw.ORCID http://orcid.org/0000-0003-2220-7574

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The repeated measurements of heart rate variability (HRV) is more relevant than a single HRV measurement in predicting patient prognosis but is less addressed previously. This prospective study aimed to investigate the association between repeated measurements of HRV and long-term mortality in chronic hemodialysis patients. The 164 patients (65.0 ± 13.1 years; woman, 57.3%) were enrolled from June 1, 2010, to August 31, 2010, and received four HRV measurements (before and during the index hemodialysis session) after the enrollment. The baseline characteristic and clinical variables, including mortality, were documented. The joint modeling method and Cox regression were used for statistical analyses. After an 8-year follow-up, 79 patients expired, and 85 patients survived. We found that higher normalized high-frequency (nHF) (hazard ratio [HR] 1.033) as well as lower very-low-frequency (HR 0.990), Variance (HR 0.991), normalized low-frequency (HR 0.999, P = 0.006), and low-frequency/high-frequency ratio (HR 0.796) were independent predictors for cardiovascular mortality. Whereas the independent predictors for infection-associated mortality included higher nHF (HR 1.033) as well as higher age (HR 19.29) and lower serum albumin (HR 0.01, P = 0.001). (all P < 0.001 unless otherwise stated) In conclusion, HRV measurement predicts long-term mortality among hemodialysis patients.

Indexed as

AgedCardiovascular DiseasesFemaleFollow-Up StudiesHeart RateHumansInfectionsKidney Failure, ChronicMaleMiddle AgedPrognosisProportional Hazards ModelsRenal Dialysis

Identifiers

PMID31964940
PMCPMC6972735

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.